Frontiers in Cardiovascular Medicine (Sep 2023)

Left atrial appendage sizing for percutaneous closure in virtual reality—a feasibility study

  • Houtan Heidari,
  • Dominika Kanschik,
  • Ralf Erkens,
  • Oliver Maier,
  • Georg Wolff,
  • Raphael Romano Bruno,
  • Nikos Werner,
  • Sebastian Daniel Reinartz,
  • Gerald Antoch,
  • Malte Kelm,
  • Malte Kelm,
  • Tobias Zeus,
  • Christian Jung,
  • Shazia Afzal,
  • Shazia Afzal

DOI
https://doi.org/10.3389/fcvm.2023.1188571
Journal volume & issue
Vol. 10

Abstract

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Background and aimsThe complex and highly variable three-dimensional anatomy of the left atrial appendage (LAA) makes planning and device sizing for interventional occlusion procedures (LAAC) challenging. Several imaging modalities [e.g. echocardiography, multi-slice computed tomography (MSCT)] are used for this purpose. Virtual reality (VR) is an emerging imaging technique to immerse into a three-dimensional left atrium and appendage, offering unprecedented options of visualization and measurement. This study aimed to investigate the feasibility, accuracy and reproducibility of visualizing the LAA in VR for preprocedural planning of LAAC.Methods and resultsTwenty-one patients (79 ± 7 years, 62% male) who underwent LAAC at University Hospital Düsseldorf were included in our study. A dedicated software generated three-dimensional VR models from preprocedural MSCT imaging data. Conventional measurements of LAA dimensions (ostium, landing zone and depth) using a commercially available software were compared to measurements in VR: MSCT and VR ostium min. (r = 0.93), max. (r = 0.80) and mean (r = 0.88, all p < 0.001) diameters as well as landing zone (LZ) min. (r = 0.84), max. (r = 0.86) and mean diameters (r = 0.90, all p < 0.001) showed strong correlations. Three-dimensional orientation was judged superior by physicians in VR compared to MSCT (p < 0.05).ConclusionVirtual reality visualization of the left atrium and appendage based on MSCT data is feasible and allows precise and reproducible measurements in planning of LAA occlusion procedures with enhanced 3D orientation. Further studies need to explore additional benefits of three-dimensional visualization for operators in preprocedural planning.

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