Journal of the Belgian Society of Radiology (Dec 2022)

Subsolid Nodule Harbouring Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue

  • Stijn Marcelis,
  • Amélie Dendooven,
  • Annemiek Snoeckx

DOI
https://doi.org/10.5334/jbsr.2915
Journal volume & issue
Vol. 106, no. 1

Abstract

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With the widespread use of computed tomography (CT), subsolid nodules are more frequently encountered in daily practice. We present the case of a 74-year-old man with a large persistent well-defined subsolid nodule on CT. Although the lesion had a predominant ground-glass appearance on CT, 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) showed moderate FDG uptake. Lobectomy was performed and histopathologic examination showed an extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue. Teaching Point: When large persistent subsolid nodule with a predominant ground-glass aspect shows moderate uptake on 18F-FDG-PET, other possible diagnoses than adenocarcinoma should be kept in mind, including primary pulmonary lymphoma.

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