Theranostics Applications of Nanoparticles in Cancer Immunotherapy

Yihai Liu; Xixi Wang; Mubashir Hussain; Mu Lv; Xiaohan Dong; Tianying Wang; Xueqin Xu; Bin Liu

doi:10.3390/medsci6040100

Medical Sciences (Nov 2018)

Theranostics Applications of Nanoparticles in Cancer Immunotherapy

Yihai Liu,
Xixi Wang,
Mubashir Hussain,
Mu Lv,
Xiaohan Dong,
Tianying Wang,
Xueqin Xu,
Bin Liu

Affiliations

Yihai Liu: Department of Biomedical Engineering, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing 211166, China
Xixi Wang: Department of Biomedical Engineering, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing 211166, China
Mubashir Hussain: State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China
Mu Lv: Department of Biomedical Engineering, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing 211166, China
Xiaohan Dong: Department of Biomedical Engineering, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing 211166, China
Tianying Wang: Department of Biomedical Engineering, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing 211166, China
Xueqin Xu: Department of Biomedical Engineering, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing 211166, China
Bin Liu: Department of Biomedical Engineering, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing 211166, China

DOI: https://doi.org/10.3390/medsci6040100
Journal volume & issue: Vol. 6, no. 4
p. 100

Abstract

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With the advancement in the mechanism of immune surveillance and immune evasion in cancer cells, cancer immunotherapy shows promising results for treating cancer with established efficacy and less toxicity. As a result of the off-target effect, the approach for delivering vaccines, adjuvants, or antibodies directly to tumor sites is gaining widespread attention. An effective alternative is to utilize nanoengineered particles, functioning as drug-delivery systems or as antigens themselves. This article reviews the practical implementation of nanotechnology in cancer immunotherapy.

Published in Medical Sciences

ISSN: 2076-3271 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine
Website: http://www.mdpi.com/journal/medsci

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