Outcome Predictors in Treatment of Yaws

Abstract

To estimate failure rates after treatment with benzathine penicillin and to identify determinants of failure that affected outcomes for yaws, we conducted a cohort study of 138 patients; treatment failed in 24 (17.4%). Having low initial titers on Venereal Disease Research Laboratory test and living in a village where yaws baseline incidence was high were associated with increased likelihood of treatment failure.

Keywords

• Yaws
• Treponema pallidum subsp. pertenue
• bacteria
• skin lesions
• serology
• treatment failure