Nature Communications (Sep 2017)

Land-locked mammalian Golgi reveals cargo transport between stable cisternae

  • Myun Hwa Dunlop,
  • Andreas M. Ernst,
  • Lena K. Schroeder,
  • Derek K. Toomre,
  • Grégory Lavieu,
  • James E. Rothman

DOI
https://doi.org/10.1038/s41467-017-00570-z
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 14

Abstract

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The different composition of Golgi cisternae gave rise to two different models for intra-Golgi traffic: one where stable cisternae communicate via vesicles and another one where cisternae biochemically mature to ensure anterograde transport. Here, the authors provide evidence in support of the stable compartments model.