486 Combined PD-L1/TGFβ blockade allows expansion and differentiation of stem cell-like CD8 T cells in immune excluded tumors

• Yagai Yang,
• Ira Mellman,
• Shannon Turley,
• Justin Elstrott,
• Alvin Gogineni,
• Zora Modrusan,
• Katherine Williams,
• Soren Muller,
• Alessandra Castiglioni,
• Jillian Astarita

Affiliations

Yagai Yang

2Genentech, Inc., South San Francisco, CA, USA

Ira Mellman

Genentech, Inc., South San Francisco, CA, USA

Shannon Turley

Genentech, South San Francisco, CA, USA

Justin Elstrott

3Genentech Research and Early Development, South San Francisco, USA

Alvin Gogineni

3Genentech Research and Early Development, South San Francisco, USA

Zora Modrusan

Department of Microchemistry, Proteomics, Lipidomics, and Next Generation Sequencing, Genentech Inc, South San Francisco, California, USA

Katherine Williams

PRODIGY communications coordinator

Soren Muller

1Genentech Inc., South San Francisco, CA, USA

Alessandra Castiglioni

2Genentech, Inc., South San Francisco, CA, USA

Jillian Astarita

2Genentech, Inc., South San Francisco, CA, USA