Primary synovial sarcoma of the brain in a 35-year-old patient: A rare clinical experience

Abstract

Synovial sarcoma is an aggressive soft-tissue sarcoma with a poor prognosis and has an origin of uncertain histology. It frequently presents as a localised disease, especially near large joints around the knee and thigh. Intracranial disease, which is rare, has been reported as a metastasis from synovial sarcoma. We report the case of a patient with no obvious primary extracranial pathology, suggesting primary intracranial synovial sarcoma. A 35-year-old male presented with altered sensorium for 1 week. Imaging was suggestive of a left frontal high-grade tumour, for which he underwent decompression. Histology showed biphasic synovial sarcoma. Positron emission tomography–computed tomography did not show lesions elsewhere. He underwent radiotherapy adjuvantly.

Keywords

• adjuvant radiation
• decompression surgery
• immunohistochemistry
• primary intracranial
• synovial sarcoma