Research progress of the role of Kisspeptin in puberty onset

ZHAO Zi-jun, MA Wei

doi:10.16352/j.issn.1001-6325.2022.10.1601

Jichu yixue yu linchuang (Oct 2022)

Research progress of the role of Kisspeptin in puberty onset

ZHAO Zi-jun, MA Wei

Affiliations

ZHAO Zi-jun, MA Wei: Department of Medicine,Northwest Minzu University,Lanzhou 730000, China

DOI: https://doi.org/10.16352/j.issn.1001-6325.2022.10.1601
Journal volume & issue: Vol. 42, no. 10
pp. 1601 – 1605

Abstract

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Kisspeptin activates the hypothalamic-pituitary-gonadal axis (HPGA) and regulates the pulsatile secretion of gonadotropin-releasing hormone (GnRH) through KNDy neurons, thereby regulating the initiation of the pubertal phase. This review focuses on the mechanism of GnRH regulation by Kisspeptin and the role of Kisspeptin in the hypothalamic, pituitary and ovarian, aiming to provide reference for clinical management of abnormal pubertal development.

puberty onset|kisspeptin|gnrh|hypothalamic pituitary gonadal axis|kndy neurons

Published in Jichu yixue yu linchuang

ISSN: 1001-6325 (Print)
Publisher: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
Country of publisher: China
LCC subjects: Medicine
Website: http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/1001-6325/home.shtml

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