Experimental Study of Ingavirin® Antiviral Activity Against Human Adenovirus

V. V. Zarubaev; A. V. Slita; A. K. Sirotkin; V. E. Nebolsin; O. I. Kiselev

Антибиотики и Химиотерапия (May 2020)

Experimental Study of Ingavirin® Antiviral Activity Against Human Adenovirus

V. V. Zarubaev,
A. V. Slita,
A. K. Sirotkin,
V. E. Nebolsin,
O. I. Kiselev

Affiliations

V. V. Zarubaev: Research Institute of Influenza, North-West Branch of the Russian Academy of Medical Sciences, St.Petersburg
A. V. Slita: Research Institute of Influenza, North-West Branch of the Russian Academy of Medical Sciences, St.Petersburg
A. K. Sirotkin: Research Institute of Influenza, North-West Branch of the Russian Academy of Medical Sciences, St.Petersburg
V. E. Nebolsin: Valenta Farm, Moscow
O. I. Kiselev: Research Institute of Influenza, North-West Branch of the Russian Academy of Medical Sciences, St.Petersburg

Journal volume & issue: Vol. 55, no. 9-10
pp. 19 – 24

Abstract

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Antiviral properties of Ingavirin® were investigated in the Hep-2 cell culture with respect to the human respiratory tract virus (type 5 adenovirus). In concentrations of Ingavirin® of 1000, 100 and 10 mcg/ml the generated posterity showed lower infective capacity (by 250, 100 and 10 times respectivelly). The electron microscopy of the infected cells confirmed the Ingavirin® ability to disturb the adenovirus normal morphogenesis.

Published in Антибиотики и Химиотерапия

ISSN: 0235-2990 (Print)
Publisher: LLC "Publishing House OKI"
Country of publisher: Russian Federation
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.antibiotics-chemotherapy.ru/

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Abstract

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