Nature Communications (Jan 2023)

Mapping nucleolus-associated chromatin interactions using nucleolus Hi-C reveals pattern of heterochromatin interactions

  • Ting Peng,
  • Yingping Hou,
  • Haowei Meng,
  • Yong Cao,
  • Xiaotian Wang,
  • Lumeng Jia,
  • Qing Chen,
  • Yang Zheng,
  • Yujie Sun,
  • Hebing Chen,
  • Tingting Li,
  • Cheng Li

DOI
https://doi.org/10.1038/s41467-023-36021-1
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 15

Abstract

Read online

Here the authors developed a nucleolus Hi-C technique (nHi-C) for enriching nucleolus-associated interactions, and revealed specific heterochromatin interaction patterns within and around nucleoli in human cells at high resolution.