A Review of the Applications of OCT for Analysing Pharmaceutical Film Coatings

Abstract

Optical coherence tomography (OCT) has recently attracted a lot of interest in the pharmaceutical manufacturing industry as a fast, contactless and non-destructive modality for quantifying thin film coatings on pharmaceutical dosage forms, which cannot be resolved easily with other techniques. In this topical review, we present an overview of the research that has been performed to date, highlighting key differences between systems and outlining major challenges ahead.

Keywords

• film coatings
• SD-OCT
• characterisation