Scientific Reports (Jun 2023)

Different intrauterine environments and children motor development in the first 6 months of life: a prospective longitudinal cohort

  • Andressa Costa Wiltgen,
  • Nadia Cristina Valentini,
  • Thiago Beltram Marcelino,
  • Luciano Santos Pinto Guimarães,
  • Clécio Homrich Da Silva,
  • Juliana Rombaldi Bernardi,
  • Marcelo Zubaran Goldani

DOI
https://doi.org/10.1038/s41598-023-36626-y
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 10

Abstract

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Abstract This prospective cohort longitudinal study examines the risk factors associated with different intrauterine environments and the influence of different intrauterine environments on children’s motor development at 3- and 6-months of life. Participants were 346 mother/newborn dyads enrolled in the first 24 to 48 h after delivery in public hospitals. Four groups with no concurrent condition composed the sample: mothers with a clinical diagnosis of diabetes, mothers with newborns small for gestational age due to idiopathic intrauterine growth restriction (IUGR), mothers who smoked tobacco during gestation, and a control group composed of mothers without clinical condition. Children were assessed at three- and six-months regarding motor development, weight, length, head circumference, and parents completed a socioeconomic questionnaire. The IUGR children had lower supine, sitting, and overall gross motor scores at 6 months than the other children’s groups. Anthropometric and sociodemographic characteristics negatively influenced gross motor development. IUGR and anthropometric and sociodemographic characteristics negatively impact motor development. Intrauterine environment impact child neurodevelopment.