Efficacy of Doramectin Via Intramuscular Injection in Gastrointestinal Nematodes in Horses

Revista de Medicina Veterinaria. 2015;0(29):41-49 DOI 10.19052/mv.3445


Journal Homepage

Journal Title: Revista de Medicina Veterinaria

ISSN: 0122-9354 (Print); 2389-8526 (Online)

Publisher: Universidad de La Salle

Society/Institution: Universidad de La Salle

LCC Subject Category: Agriculture: Animal culture: Veterinary medicine

Country of publisher: Colombia

Language of fulltext: English, Spanish

Full-text formats available: PDF



Yonairo Manuel Herrera Benavides (Estudiante de Maestría en Ciencias Veterinarias del Trópico, Universidad de Córdoba, Montería)

Sandra Carolina Perdomo Ayola (Estudiante de Maestría en Ciencias Veterinarias del Trópico, Universidad de Córdoba)

José Alberto Cardona Álvarez (Medicina y Clínica de Grandes Animales. Semillero de estudios e investigaciones en Medicina de Grandes Animales, grupo MEGA, Universidad de Córdoba, Montería)


Double blind peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 16 weeks


Abstract | Full Text

This research aimed to test the effectiveness of doramectin by intramuscular administration against nematodes of horses, as it is evacuated, observed in the reduction in egg counts per gram of feces (epg). To this end, six donkeys and ten mestizo horses of different sexes and ages were used, all naturally infected with gastrointestinal nematodes. Animals were randomly divided into two groups: 1 (control), three donkeys and four horses that didn’t receive anthelmintic treatment; and 2 (treated), three donkeys and six horses treated with doramectin at a dose of 0.2 mg/kg by intramuscular administration, single dose, applied on the neck. At days 5, 12, 16, 24, 34, 41, 47, 56, 60 and 140 post-treatment all animals were subjected to stool tests, allowing to define epg values by McMaster technique. The results determined that doramectin by intramuscular administration was highly effective in controlling nematodes in field conditions and in animals subjected to continual reinfestation.