Spatiotemporal depletion of tumor-associated immune checkpoint PD-L1 with near-infrared photoimmunotherapy promotes antitumor immunity

• Shunichi Taki,
• Kohei Matsuoka,
• Yuko Nishinaga,
• Kazuomi Takahashi,
• Hirotoshi Yasui,
• Chiaki Koike,
• Misae Shimizu,
• Mitsuo Sato,
• Kazuhide Sato

Affiliations

Shunichi Taki

Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, AICHI, Japan

Kohei Matsuoka

Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, AICHI, Japan

Yuko Nishinaga

Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, AICHI, Japan

Kazuomi Takahashi

Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, AICHI, Japan

Hirotoshi Yasui

Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, AICHI, Japan

Chiaki Koike

Advanced Analytical and Diagnostic Imaging Center (AADIC) / Medical Engineering Unit (MEU), B3 Unit, Nagoya University Institute for Advanced Research, Nagoya, AICHI, Japan

Misae Shimizu

Advanced Analytical and Diagnostic Imaging Center (AADIC) / Medical Engineering Unit (MEU), B3 Unit, Nagoya University Institute for Advanced Research, Nagoya, AICHI, Japan

Mitsuo Sato

Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, AICHI, Japan

Kazuhide Sato

Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, AICHI, Japan