Current discourse on recurrent pregnancy loss (ESHRE Protocol 2023, National Clinical Guidelines "Recurrent Pregnancy Loss" 2021, materials of the World Congress of ESHRE 2023)

Abstract

Yu.E. Dobrokhotova, P.A. Kuznetsov, L.S. Dzhokhadze Pirogov Russian National Research Medical University, Moscow, Russian Federation In January 2023, European Society of Human Reproduction and Embryology (ESHRE) has released updated recommendations on recurrent pregnancy loss to replace the previous 2017 version. All changes and addendum to the recommendations in the guidelines were formulated after evaluating the most qualitative and relevant evidence that appeared in the literature and their discussion by an expert group. The authors of this article have analyzed the main points of the updated ESHRE recommendations. The article discusses whether new tactics have appeared in the patient management with recurrent pregnancy loss, whether they should be adopted by a practicing physician, and whether they differ from the recommendations of the Russian Society of Obstetricians and Gynecologists regulating the actions of Russian medical specialists during the work with female patients having the appropriate diagnosis. Based on the analysis, the authors concluded that the expert groups that compiled clinical recommendations on recurrent pregnancy loss are mostly in solidarity on fundamental issues. On the one hand, the Russian recommendations look more reasonable in some issues, but on the other, the recommendations are likely to be revised taking into account new data. Keywords: recurrent pregnancy loss, habitual abortion, pregnancy, ESHRE, clinical recommendations, RSOG, assisted reproductive technologies. For citation: Dobrokhotova Yu.E., Kuznetsov P.A., Dzhokhadze L.S. Current discourse on recurrent pregnancy loss (ESHRE Protocol 2023, National Clinical Guidelines "Recurrent Pregnancy Loss" 2021, materials of the World Congress of ESHRE 2023). Russian Journal of Woman and Child Health. 2023;6(3):2019–225 (in Russ.). DOI: 10.32364/2618-8430-2023-6-3-1.