Bioactive Compound-Loaded Nanocarriers for Hair Growth Promotion: Current Status and Future Perspectives
Arvind Sharma,
Harapriya Mohapatra,
Kanika Arora,
Ritchu Babbar,
Rashmi Arora,
Poonam Arora,
Pradeep Kumar,
Evren Algın Yapar,
Kailash Rani,
Maninder Meenu,
Marianesan Arockia Babu,
Maninderjit Kaur,
Rakesh K. Sindhu
Affiliations
Arvind Sharma
School of Pharmaceutical and Health Sciences, Bhoranj (Tikker–Kharwarian), Hamirpur 176041, India
Harapriya Mohapatra
Chitkara College of Pharmacy, Chitkara University, Rajpura 140401, India
Kanika Arora
Chitkara College of Pharmacy, Chitkara University, Rajpura 140401, India
Ritchu Babbar
Chitkara College of Pharmacy, Chitkara University, Rajpura 140401, India
Rashmi Arora
Chitkara College of Pharmacy, Chitkara University, Rajpura 140401, India
Poonam Arora
Chitkara College of Pharmacy, Chitkara University, Rajpura 140401, India
Pradeep Kumar
Wits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, 7 York Road, Parktown, Johannesburg 2193, South Africa
Evren Algın Yapar
Faculty of Pharmacy, Sivas Cumhuriyet University, Sivas 58140, Türkiye
Kailash Rani
Chitkara College of Pharmacy, Chitkara University, Rajpura 140401, India
Maninder Meenu
Department of Agri-Biotechnology, National Agri-Food Biotechnology Institute, Mohali 143005, India
Marianesan Arockia Babu
Institute of Pharmaceutical Research, GLA University, Mathura 281406, India
Maninderjit Kaur
Department of Pharmaceutical Sciences, Lovely Professional University, Phagwara 144411, India
Rakesh K. Sindhu
School of Pharmacy, Sharda University, Greater Noida 201306, India
Hair loss (alopecia) has a multitude of causes, and the problem is still poorly defined. For curing alopecia, therapies are available in both natural and synthetic forms; however, natural remedies are gaining popularity due to the multiple effects of complex phytoconstituents on the scalp with fewer side effects. Evidence-based hair growth promotion by some plants has been reported for both traditional and advanced treatment approaches. Nanoarchitectonics may have the ability to evolve in the field of hair- and scalp-altering products and treatments, giving new qualities to hair that can be an effective protective layer or a technique to recover lost hair. This review will provide insights into several plant and herbal formulations that have been reported for the prevention of hair loss and stimulation of new hair growth. This review also focuses on the molecular mechanisms of hair growth/loss, several isolated phytoconstituents with hair growth-promoting properties, patents, in vivo evaluation of hair growth-promoting activity, and recent nanoarchitectonic technologies that have been explored for hair growth.
