Photodiagnosis and Photodynamic Therapy (Apr 2025)

Effects of repeated low-level red-light therapy on myopia control in children with intermittent exotropia

  • Yichao Qian,
  • Xiangyun Li,
  • Yawen Zhu,
  • Xiaoli Qi,
  • Gang Yu,
  • Feng Zhang,
  • Lili Guo,
  • Wenjing Ku,
  • Xuehan Qian

DOI
https://doi.org/10.1016/j.pdpdt.2025.104526
Journal volume & issue
Vol. 52
p. 104526

Abstract

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Background: The optimal myopia control measures for children with intermittent exotropia (IXT) have yet to be determined. This study evaluates the impact of Repeated low-level red-light therapy (RLRL) on myopia control in this population. Methods: This retrospective study included 94 participants divided into three groups: Myopic children without strabismus receiving RLRL treatment (RLRL Group).Children with IXT and myopia undergoing RLRL treatment (IXT with RLRL Group).ChJournal Titleildren with IXT and myopia not receiving any myopia control interventions(Control Group).Axial length (AL) and spherical equivalent refraction (SER) were measured before and after the intervention. For patients with IXT, distance and near exodeviation angles and near stereopsis were also assessed. Results: Post-RLRL treatment, the IXT with RLRL Group exhibited significantly less AL elongation compared to the Control Group at various time points (P0.05). Additionally, no significant differences in AL and SER control were observed between the IXT with RLRL Group and the RLRL Group (P>0.05), and treatment efficacy was similar between the two eyes. Conclusions: RLRL is effective in controlling myopia progression in children with IXT without adversely affecting strabismus parameters. Its efficacy is comparable to that observed in children without strabismus, suggesting RLRL as a viable option for myopia management in this population.

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