Radiology Case Reports (Mar 2022)

Retroperitoneal ganglioneuroma in a 15-year-old boy, an interesting case studied through multimodal imaging

  • Carmela Falcone, MD, PhD,
  • Giulia Adriana Calafiore, MD,
  • Lucia Paola Vazzana, MD,
  • Lara Natoli, MD,
  • Pietro Arciello, MD,
  • Claudio Franzutti, MD,
  • Caterina Tripodi, MD,
  • Giuseppe Ielo, MD

Journal volume & issue
Vol. 17, no. 3
pp. 450 – 454

Abstract

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Benign ganglioneuroma contains mature autonomous ganglion cells, including satellite cells and long axonal processes, as well as Schwann cells, which come from neural crest-derived cells that form the adrenal medulla and sympathetic nervous system during embryonic development and is a rare benign tumor which occurs spontaneously and can also occur during radiotherapy or chemotherapy, accounting for 0.72% -1.6% of primary retroperitoneal tumors, commonly found in the posterior mediastinum and retroperitoneum, and affected patients usually have no symptoms due to of its non-functional feature, although several complications can arise if the tumor is large enough to press against adjacent organs.

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