Synthesis and Biological Significance of Some 2-Azetidinone Derivatives

Abstract

A new series of N-[2-(1H-1,2,3-benzotriazol-1-yl)ethyl]-4-(substitutedphenyl)-3-chloro-2-oxo-1-iminoazetidine, compounds 4(a-j) were synthesized. The structures of all the synthesized compounds were confirmed by chemical and spectral analyses such as IR, 1H NMR, 13C NMR and FAB-Mass. The compounds 4(a-j) were screened for their antibacterial, antifungal and antitubercular activities and gave acceptable results.

Keywords

• 2
• 3-benzotriazole
• antitubercular
• synthesis
• 1
• azetidinone
• antimicrobial