Nature Communications (Oct 2019)
Associations of autozygosity with a broad range of human phenotypes
- David W Clark,
- Yukinori Okada,
- Kristjan H S Moore,
- Dan Mason,
- Nicola Pirastu,
- Ilaria Gandin,
- Hannele Mattsson,
- Catriona L K Barnes,
- Kuang Lin,
- Jing Hua Zhao,
- Patrick Deelen,
- Rebecca Rohde,
- Claudia Schurmann,
- Xiuqing Guo,
- Franco Giulianini,
- Weihua Zhang,
- Carolina Medina-Gomez,
- Robert Karlsson,
- Yanchun Bao,
- Traci M Bartz,
- Clemens Baumbach,
- Ginevra Biino,
- Matthew J Bixley,
- Marco Brumat,
- Jin-Fang Chai,
- Tanguy Corre,
- Diana L Cousminer,
- Annelot M Dekker,
- David A Eccles,
- Kristel R van Eijk,
- Christian Fuchsberger,
- He Gao,
- Marine Germain,
- Scott D Gordon,
- Hugoline G de Haan,
- Sarah E Harris,
- Edith Hofer,
- Alicia Huerta-Chagoya,
- Catherine Igartua,
- Iris E Jansen,
- Yucheng Jia,
- Tim Kacprowski,
- Torgny Karlsson,
- Marcus E Kleber,
- Shengchao Alfred Li,
- Ruifang Li-Gao,
- Anubha Mahajan,
- Koichi Matsuda,
- Karina Meidtner,
- Weihua Meng,
- May E Montasser,
- Peter J van der Most,
- Matthias Munz,
- Teresa Nutile,
- Teemu Palviainen,
- Gauri Prasad,
- Rashmi B Prasad,
- Tallapragada Divya Sri Priyanka,
- Federica Rizzi,
- Erika Salvi,
- Bishwa R Sapkota,
- Daniel Shriner,
- Line Skotte,
- Melissa C Smart,
- Albert Vernon Smith,
- Ashley van der Spek,
- Cassandra N Spracklen,
- Rona J Strawbridge,
- Salman M Tajuddin,
- Stella Trompet,
- Constance Turman,
- Niek Verweij,
- Clara Viberti,
- Lihua Wang,
- Helen R Warren,
- Robyn E Wootton,
- Lisa R Yanek,
- Jie Yao,
- Noha A Yousri,
- Wei Zhao,
- Adebowale A Adeyemo,
- Saima Afaq,
- Carlos Alberto Aguilar-Salinas,
- Masato Akiyama,
- Matthew L Albert,
- Matthew A Allison,
- Maris Alver,
- Tin Aung,
- Fereidoun Azizi,
- Amy R Bentley,
- Heiner Boeing,
- Eric Boerwinkle,
- Judith B Borja,
- Gert J de Borst,
- Erwin P Bottinger,
- Linda Broer,
- Harry Campbell,
- Stephen Chanock,
- Miao-Li Chee,
- Guanjie Chen,
- Yii-Der I Chen,
- Zhengming Chen,
- Yen-Feng Chiu,
- Massimiliano Cocca,
- Francis S Collins,
- Maria Pina Concas,
- Janie Corley,
- Giovanni Cugliari,
- Rob M van Dam,
- Anna Damulina,
- Maryam S Daneshpour,
- Felix R Day,
- Graciela E Delgado,
- Klodian Dhana,
- Alexander S F Doney,
- Marcus Dörr,
- Ayo P Doumatey,
- Nduna Dzimiri,
- S Sunna Ebenesersdóttir,
- Joshua Elliott,
- Paul Elliott,
- Ralf Ewert,
- Janine F Felix,
- Krista Fischer,
- Barry I Freedman,
- Giorgia Girotto,
- Anuj Goel,
- Martin Gögele,
- Mark O Goodarzi,
- Mariaelisa Graff,
- Einat Granot-Hershkovitz,
- Francine Grodstein,
- Simonetta Guarrera,
- Daniel F Gudbjartsson,
- Kamran Guity,
- Bjarni Gunnarsson,
- Yu Guo,
- Saskia P Hagenaars,
- Christopher A Haiman,
- Avner Halevy,
- Tamara B Harris,
- Mehdi Hedayati,
- David A van Heel,
- Makoto Hirata,
- Imo Höfer,
- Chao Agnes Hsiung,
- Jinyan Huang,
- Yi-Jen Hung,
- M Arfan Ikram,
- Anuradha Jagadeesan,
- Pekka Jousilahti,
- Yoichiro Kamatani,
- Masahiro Kanai,
- Nicola D Kerrison,
- Thorsten Kessler,
- Kay-Tee Khaw,
- Chiea Chuen Khor,
- Dominique P V de Kleijn,
- Woon-Puay Koh,
- Ivana Kolcic,
- Peter Kraft,
- Bernhard K Krämer,
- Zoltán Kutalik,
- Johanna Kuusisto,
- Claudia Langenberg,
- Lenore J Launer,
- Deborah A Lawlor,
- I-Te Lee,
- Wen-Jane Lee,
- Markus M Lerch,
- Liming Li,
- Jianjun Liu,
- Marie Loh,
- Stephanie J London,
- Stephanie Loomis,
- Yingchang Lu,
- Jian’an Luan,
- Reedik Mägi,
- Ani W Manichaikul,
- Paolo Manunta,
- Gísli Másson,
- Nana Matoba,
- Xue W Mei,
- Christa Meisinger,
- Thomas Meitinger,
- Massimo Mezzavilla,
- Lili Milani,
- Iona Y Millwood,
- Yukihide Momozawa,
- Amy Moore,
- Pierre-Emmanuel Morange,
- Hortensia Moreno-Macías,
- Trevor A Mori,
- Alanna C Morrison,
- Taulant Muka,
- Yoshinori Murakami,
- Alison D Murray,
- Renée de Mutsert,
- Josyf C Mychaleckyj,
- Mike A Nalls,
- Matthias Nauck,
- Matt J Neville,
- Ilja M Nolte,
- Ken K Ong,
- Lorena Orozco,
- Sandosh Padmanabhan,
- Gunnar Pálsson,
- James S Pankow,
- Cristian Pattaro,
- Alison Pattie,
- Ozren Polasek,
- Neil Poulter,
- Peter P Pramstaller,
- Lluis Quintana-Murci,
- Katri Räikkönen,
- Sarju Ralhan,
- Dabeeru C Rao,
- Wouter van Rheenen,
- Stephen S Rich,
- Paul M Ridker,
- Cornelius A Rietveld,
- Antonietta Robino,
- Frank J A van Rooij,
- Daniela Ruggiero,
- Yasaman Saba,
- Charumathi Sabanayagam,
- Maria Sabater-Lleal,
- Cinzia Felicita Sala,
- Veikko Salomaa,
- Kevin Sandow,
- Helena Schmidt,
- Laura J Scott,
- William R Scott,
- Bahareh Sedaghati-Khayat,
- Bengt Sennblad,
- Jessica van Setten,
- Peter J Sever,
- Wayne H-H Sheu,
- Yuan Shi,
- Smeeta Shrestha,
- Sharvari Rahul Shukla,
- Jon K Sigurdsson,
- Timo Tonis Sikka,
- Jai Rup Singh,
- Blair H Smith,
- Alena Stančáková,
- Alice Stanton,
- John M Starr,
- Lilja Stefansdottir,
- Leon Straker,
- Patrick Sulem,
- Gardar Sveinbjornsson,
- Morris A Swertz,
- Adele M Taylor,
- Kent D Taylor,
- Natalie Terzikhan,
- Yih-Chung Tham,
- Gudmar Thorleifsson,
- Unnur Thorsteinsdottir,
- Annika Tillander,
- Russell P Tracy,
- Teresa Tusié-Luna,
- Ioanna Tzoulaki,
- Simona Vaccargiu,
- Jagadish Vangipurapu,
- Jan H Veldink,
- Veronique Vitart,
- Uwe Völker,
- Eero Vuoksimaa,
- Salma M Wakil,
- Melanie Waldenberger,
- Gurpreet S Wander,
- Ya Xing Wang,
- Nicholas J Wareham,
- Sarah Wild,
- Chittaranjan S Yajnik,
- Jian-Min Yuan,
- Lingyao Zeng,
- Liang Zhang,
- Jie Zhou,
- Najaf Amin,
- Folkert W Asselbergs,
- Stephan J L Bakker,
- Diane M Becker,
- Benjamin Lehne,
- David A Bennett,
- Leonard H van den Berg,
- Sonja I Berndt,
- Dwaipayan Bharadwaj,
- Lawrence F Bielak,
- Murielle Bochud,
- Mike Boehnke,
- Claude Bouchard,
- Jonathan P Bradfield,
- Jennifer A Brody,
- Archie Campbell,
- Shai Carmi,
- Mark J Caulfield,
- David Cesarini,
- John C Chambers,
- Giriraj Ratan Chandak,
- Ching-Yu Cheng,
- Marina Ciullo,
- Marilyn Cornelis,
- Daniele Cusi,
- George Davey Smith,
- Ian J Deary,
- Rajkumar Dorajoo,
- Cornelia M van Duijn,
- David Ellinghaus,
- Jeanette Erdmann,
- Johan G Eriksson,
- Evangelos Evangelou,
- Michele K Evans,
- Jessica D Faul,
- Bjarke Feenstra,
- Mary Feitosa,
- Sylvain Foisy,
- Andre Franke,
- Yechiel Friedlander,
- Paolo Gasparini,
- Christian Gieger,
- Clicerio Gonzalez,
- Philippe Goyette,
- Struan F A Grant,
- Lyn R Griffiths,
- Leif Groop,
- Vilmundur Gudnason,
- Ulf Gyllensten,
- Hakon Hakonarson,
- Anders Hamsten,
- Pim van der Harst,
- Chew-Kiat Heng,
- Andrew A Hicks,
- Hagit Hochner,
- Heikki Huikuri,
- Steven C Hunt,
- Vincent W V Jaddoe,
- Philip L De Jager,
- Magnus Johannesson,
- Åsa Johansson,
- Jost B Jonas,
- J Wouter Jukema,
- Juhani Junttila,
- Jaakko Kaprio,
- Sharon L. R. Kardia,
- Fredrik Karpe,
- Meena Kumari,
- Markku Laakso,
- Sander W van der Laan,
- Jari Lahti,
- Matthias Laudes,
- Rodney A Lea,
- Wolfgang Lieb,
- Thomas Lumley,
- Nicholas G Martin,
- Winfried März,
- Giuseppe Matullo,
- Mark I McCarthy,
- Sarah E Medland,
- Tony R Merriman,
- Andres Metspalu,
- Brian F Meyer,
- Karen L Mohlke,
- Grant W Montgomery,
- Dennis Mook-Kanamori,
- Patricia B Munroe,
- Kari E North,
- Dale R Nyholt,
- Jeffery R O’connell,
- Carole Ober,
- Albertine J Oldehinkel,
- Walter Palmas,
- Colin Palmer,
- Gerard G Pasterkamp,
- Etienne Patin,
- Craig E Pennell,
- Louis Perusse,
- Patricia A Peyser,
- Mario Pirastu,
- Tinca J. C. Polderman,
- David J Porteous,
- Danielle Posthuma,
- Bruce M Psaty,
- John D Rioux,
- Fernando Rivadeneira,
- Charles Rotimi,
- Jerome I Rotter,
- Igor Rudan,
- Hester M Den Ruijter,
- Dharambir K Sanghera,
- Naveed Sattar,
- Reinhold Schmidt,
- Matthias B Schulze,
- Heribert Schunkert,
- Robert A Scott,
- Alan R Shuldiner,
- Xueling Sim,
- Neil Small,
- Jennifer A Smith,
- Nona Sotoodehnia,
- E-Shyong Tai,
- Alexander Teumer,
- Nicholas J Timpson,
- Daniela Toniolo,
- David-Alexandre Tregouet,
- Tiinamaija Tuomi,
- Peter Vollenweider,
- Carol A Wang,
- David R Weir,
- John B Whitfield,
- Cisca Wijmenga,
- Tien-Yin Wong,
- John Wright,
- Jingyun Yang,
- Lei Yu,
- Babette S Zemel,
- Alan B Zonderman,
- Markus Perola,
- Patrik K. E. Magnusson,
- André G Uitterlinden,
- Jaspal S Kooner,
- Daniel I Chasman,
- Ruth J. F. Loos,
- Nora Franceschini,
- Lude Franke,
- Chris S Haley,
- Caroline Hayward,
- Robin G Walters,
- John R. B. Perry,
- Tōnu Esko,
- Agnar Helgason,
- Kari Stefansson,
- Peter K Joshi,
- Michiaki Kubo,
- James F Wilson
Affiliations
- David W Clark
- Centre for Global Health Research, Usher Institute, University of Edinburgh
- Yukinori Okada
- Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita
- Kristjan H S Moore
- deCODE genetics/Amgen Inc.
- Dan Mason
- Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Trust
- Nicola Pirastu
- Centre for Global Health Research, Usher Institute, University of Edinburgh
- Ilaria Gandin
- Research Unit, Area Science Park
- Hannele Mattsson
- Unit of Public Health Solutions, National Institute for Health and Welfare
- Catriona L K Barnes
- Centre for Global Health Research, Usher Institute, University of Edinburgh
- Kuang Lin
- Nuffield Department of Population Health, University of Oxford
- Jing Hua Zhao
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine
- Patrick Deelen
- Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands, Groningen
- Rebecca Rohde
- Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina
- Claudia Schurmann
- The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai
- Xiuqing Guo
- Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance
- Franco Giulianini
- Division of Preventive Medicine, Brigham and Women’s Hospital
- Weihua Zhang
- Department of Epidemiology and Biostatistics, Imperial College London
- Carolina Medina-Gomez
- Department of Internal Medicine, Erasmus University Medical Center
- Robert Karlsson
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
- Yanchun Bao
- Institute for Social and Economic Research, University of Essex
- Traci M Bartz
- Cardiovascular Health Research Unit, Departments of Biostatistics and Medicine, University of Washington
- Clemens Baumbach
- Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health
- Ginevra Biino
- Institute of Molecular Genetics, National Research Council of Italy
- Matthew J Bixley
- Department of Biochemistry, University of Otago
- Marco Brumat
- Department of Medicine, Surgery and Health Sciences, University of Trieste
- Jin-Fang Chai
- Saw Swee Hock School of Public Health, National University of Singapore, Singapore
- Tanguy Corre
- Department of Computational Biology, University of Lausanne
- Diana L Cousminer
- Division of Human Genetics, Children’s Hospital of Philadelphia
- Annelot M Dekker
- Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht University
- David A Eccles
- Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology
- Kristel R van Eijk
- Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht University
- Christian Fuchsberger
- Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck
- He Gao
- Department of Epidemiology and Biostatistics, Imperial College London
- Marine Germain
- INSERM UMR_S 1166, Sorbonne Universités
- Scott D Gordon
- QIMR Berghofer Institute of Medical Research
- Hugoline G de Haan
- Department of Clinical Epidemiology, Leiden University Medical Center
- Sarah E Harris
- Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh
- Edith Hofer
- Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz
- Alicia Huerta-Chagoya
- CONACyT, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
- Catherine Igartua
- Department of Human Genetics, University of Chicago
- Iris E Jansen
- Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam
- Yucheng Jia
- Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance
- Tim Kacprowski
- Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald
- Torgny Karlsson
- Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University
- Marcus E Kleber
- Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Heidelberg University
- Shengchao Alfred Li
- Cancer Genomics Research Laboratory, Leidos Biomedical Research, Inc., Frederick National Lab for Cancer Research
- Ruifang Li-Gao
- Department of Clinical Epidemiology, Leiden University Medical Center
- Anubha Mahajan
- Wellcome Centre for Human Genetics, University of Oxford
- Koichi Matsuda
- Department of Computational Biology and Medical Sciences, Graduate school of Frontier Sciences, The University of Tokyo
- Karina Meidtner
- Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke
- Weihua Meng
- Medical Research Institute, Ninewells Hospital and School of Medicine, University of Dundee
- May E Montasser
- Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland, School of Medicine
- Peter J van der Most
- Department of Epidemiology, University of Groningen, University Medical Center Groningen
- Matthias Munz
- Institute for Cardiogenetics, University of Lübeck
- Teresa Nutile
- Institute of Genetics and Biophysics A. Buzzati-Traverso - CNR
- Teemu Palviainen
- Finnish Institute for Molecular Medicine, University of Helsinki
- Gauri Prasad
- Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology
- Rashmi B Prasad
- Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Lund University, Skåne University Hospital
- Tallapragada Divya Sri Priyanka
- Genomic Research on Complex diseases (GRC Group), CSIR-Centre for Cellular and Molecular Biology
- Federica Rizzi
- ePhood Scientific Unit, ePhood SRL
- Erika Salvi
- Department of Health Sciences, University of Milano
- Bishwa R Sapkota
- Department of Pediatrics, College of Medicine, University of Oklahoma Health Sciences Center
- Daniel Shriner
- Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health
- Line Skotte
- Department of Epidemiology Research, Statens Serum Institut
- Melissa C Smart
- Institute for Social and Economic Research, University of Essex
- Albert Vernon Smith
- Icelandic Heart Association
- Ashley van der Spek
- Department of Epidemiology, Erasmus University Medical Center
- Cassandra N Spracklen
- Department of Genetics, University of North Carolina
- Rona J Strawbridge
- Institute of Health and Wellbeing, University of Glasgow
- Salman M Tajuddin
- Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health
- Stella Trompet
- Department of Cardiology, Leiden University Medical Center
- Constance Turman
- Department of Epidemiology, Harvard T.H. Chan School of Public Health
- Niek Verweij
- University of Groningen, University Medical Center Groningen, Department of Cardiology, Ther Netherlands
- Clara Viberti
- Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences, University of Turin, Italy
- Lihua Wang
- Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine
- Helen R Warren
- NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London
- Robyn E Wootton
- MRC Integrative Epidemiology Unit at the University of Bristol
- Lisa R Yanek
- Department of Medicine, GeneSTAR Research Program, Johns Hopkins University School of Medicine
- Jie Yao
- Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance
- Noha A Yousri
- Department of Genetic Medicine, Weill Cornell Medicine Qatar
- Wei Zhao
- Department of Epidemiology, School of Public Health, University of Michigan
- Adebowale A Adeyemo
- Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health
- Saima Afaq
- Department of Epidemiology and Biostatistics, Imperial College London
- Carlos Alberto Aguilar-Salinas
- Departamento de Endocrinología y Metabolismo, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
- Masato Akiyama
- Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences
- Matthew L Albert
- Immunobiology of Dendritic Cells, Institut Pasteur
- Matthew A Allison
- Division of Preventive Medicine, Department of Family Medicine and Public Health, UC San Diego School of Medicine
- Maris Alver
- Estonian Genome Center, University of Tartu, University of Tartu
- Tin Aung
- Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
- Fereidoun Azizi
- Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences
- Amy R Bentley
- Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health
- Heiner Boeing
- Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke
- Eric Boerwinkle
- Health Science Center at Houston, UTHealth School of Public Health, University of Texas
- Judith B Borja
- USC-Office of Population Studies Foundation, Inc., Department of Nutrition and Dietetics, Talamban, University of San Carlos
- Gert J de Borst
- Department of Vascular Surgery, Division of Surgical Specialties, University Medical Center Utrecht, University of Utrecht, Utrecht
- Erwin P Bottinger
- The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai
- Linda Broer
- Department of Internal Medicine, Erasmus University Medical Center
- Harry Campbell
- Centre for Global Health Research, Usher Institute, University of Edinburgh
- Stephen Chanock
- Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health
- Miao-Li Chee
- Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
- Guanjie Chen
- Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health
- Yii-Der I Chen
- Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance
- Zhengming Chen
- Nuffield Department of Population Health, University of Oxford
- Yen-Feng Chiu
- Institute of Population Health Sciences, National Health Research Institutes
- Massimiliano Cocca
- Institute for Maternal and Child Health - IRCCS Burlo Garofolo
- Francis S Collins
- National Human Genome Research Institute, National Institutes of Health
- Maria Pina Concas
- Institute for Maternal and Child Health - IRCCS Burlo Garofolo
- Janie Corley
- Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh
- Giovanni Cugliari
- Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences, University of Turin, Italy
- Rob M van Dam
- Saw Swee Hock School of Public Health, National University of Singapore, Singapore
- Anna Damulina
- Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz
- Maryam S Daneshpour
- Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences
- Felix R Day
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine
- Graciela E Delgado
- Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Heidelberg University
- Klodian Dhana
- Department of Epidemiology, Erasmus University Medical Center
- Alexander S F Doney
- MEMO Research, Molecular and Clinical Medicine, University of Dundee
- Marcus Dörr
- Department of Internal Medicine B, University Medicine Greifswald
- Ayo P Doumatey
- Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health
- Nduna Dzimiri
- Department of Genetics, King Faisal Specialist Hospital and Research Center
- S Sunna Ebenesersdóttir
- deCODE genetics/Amgen Inc.
- Joshua Elliott
- Department of Epidemiology and Biostatistics, Imperial College London
- Paul Elliott
- Department of Epidemiology and Biostatistics, Imperial College London
- Ralf Ewert
- Department of Internal Medicine B, University Medicine Greifswald
- Janine F Felix
- Department of Epidemiology, Erasmus University Medical Center
- Krista Fischer
- Estonian Genome Center, University of Tartu, University of Tartu
- Barry I Freedman
- Section on Nephrology, Department of Internal Medicine, Wake Forest School of Medicine
- Giorgia Girotto
- Department of Medicine, Surgery and Health Sciences, University of Trieste
- Anuj Goel
- Wellcome Centre for Human Genetics, University of Oxford
- Martin Gögele
- Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck
- Mark O Goodarzi
- Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Cedars-Sinai Medical Center
- Mariaelisa Graff
- Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina
- Einat Granot-Hershkovitz
- Braun School of Public Health, Hebrew University-Hadassah Medical Center
- Francine Grodstein
- Department of Epidemiology, Harvard T.H. Chan School of Public Health
- Simonetta Guarrera
- Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences, University of Turin, Italy
- Daniel F Gudbjartsson
- deCODE genetics/Amgen Inc.
- Kamran Guity
- Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences
- Bjarni Gunnarsson
- deCODE genetics/Amgen Inc.
- Yu Guo
- Chinese Academy of Medical Sciences
- Saskia P Hagenaars
- Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh
- Christopher A Haiman
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California
- Avner Halevy
- Braun School of Public Health, Hebrew University-Hadassah Medical Center
- Tamara B Harris
- Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health
- Mehdi Hedayati
- Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences
- David A van Heel
- Blizard Institute, Queen Mary University of London
- Makoto Hirata
- Laboratory of Genome Technology, Institute of Medical Science, The University of Tokyo
- Imo Höfer
- Laboratory of Clinical Chemistry and Hematology, Division Laboratories and Pharmacy, University Medical Center Utrecht, University of Utrecht, Utrecht
- Chao Agnes Hsiung
- Institute of Population Health Sciences, National Health Research Institutes
- Jinyan Huang
- Shanghai Institute of Hematology, State Key Laboratory Of Medical Genomics, Rui-jin Hospital, Shanghai Jiao Tong University School of Medicine
- Yi-Jen Hung
- Division of Endocrine and Metabolism, Tri-Service General Hospital Songshan branch
- M Arfan Ikram
- Department of Epidemiology, Erasmus University Medical Center
- Anuradha Jagadeesan
- deCODE genetics/Amgen Inc.
- Pekka Jousilahti
- Unit of Public Health Promotion, National Institute for Health and Welfare
- Yoichiro Kamatani
- Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences
- Masahiro Kanai
- Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita
- Nicola D Kerrison
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine
- Thorsten Kessler
- Deutsches Herzzentrum München, Klinik für Herz- und Kreislauferkrankungen, Technische Universität München
- Kay-Tee Khaw
- Department of Public Health and Primary Care, University of Cambridge
- Chiea Chuen Khor
- Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
- Dominique P V de Kleijn
- Department of Vascular Surgery, Division of Surgical Specialties, University Medical Center Utrecht, University of Utrecht, Utrecht
- Woon-Puay Koh
- Saw Swee Hock School of Public Health, National University of Singapore, Singapore
- Ivana Kolcic
- Centre for Global Health, Faculty of Medicine, University of Split
- Peter Kraft
- Department of Nutrition, Harvard T.H. Chan School of Public Health
- Bernhard K Krämer
- Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Heidelberg University
- Zoltán Kutalik
- Center for Primary Care and Public Health (Unisanté), University of Lausanne
- Johanna Kuusisto
- Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland
- Claudia Langenberg
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine
- Lenore J Launer
- Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health
- Deborah A Lawlor
- MRC Integrative Epidemiology Unit at the University of Bristol
- I-Te Lee
- Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital
- Wen-Jane Lee
- Department of Medical Research, Taichung Veterans General Hospital
- Markus M Lerch
- Department of Internal Medicine A, University Medicine Greifswald
- Liming Li
- Department of Epidemiology and Biostatistics, Peking University Health Science Centre, Peking University
- Jianjun Liu
- Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore
- Marie Loh
- Department of Epidemiology and Biostatistics, Imperial College London
- Stephanie J London
- National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services
- Stephanie Loomis
- Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health
- Yingchang Lu
- The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai
- Jian’an Luan
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine
- Reedik Mägi
- Estonian Genome Center, University of Tartu, University of Tartu
- Ani W Manichaikul
- Center for Public Health Genomics, University of Virginia School of Medicine
- Paolo Manunta
- Genomics of Renal Diseases and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Università Vita Salute San Raffaele
- Gísli Másson
- deCODE genetics/Amgen Inc.
- Nana Matoba
- Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences
- Xue W Mei
- Nuffield Department of Population Health, University of Oxford
- Christa Meisinger
- Helmholtz Zentrum München, Independent Research Group Clinical Epidemiology
- Thomas Meitinger
- Institute of Human Genetics, Helmholtz Zentrum Muenchen
- Massimo Mezzavilla
- Medical Genetics, Institute for Maternal and Child Health - IRCCS Burlo Garofolo
- Lili Milani
- Estonian Genome Center, Institute of Genomics, University of Tartu
- Iona Y Millwood
- Nuffield Department of Population Health, University of Oxford
- Yukihide Momozawa
- Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences
- Amy Moore
- Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health
- Pierre-Emmanuel Morange
- Laboratory of Haematology, La Timone Hospital
- Hortensia Moreno-Macías
- Departamento de Economía, Universidad Autónoma Metropolitana
- Trevor A Mori
- Medical School, The University of Western Australia
- Alanna C Morrison
- The University of Texas Health Science Center at Houston, School of Public Health, Department of Epidemiology, Human Genetics and Environmental Sciences
- Taulant Muka
- Department of Epidemiology, Erasmus University Medical Center
- Yoshinori Murakami
- Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo
- Alison D Murray
- The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen
- Renée de Mutsert
- Department of Clinical Epidemiology, Leiden University Medical Center
- Josyf C Mychaleckyj
- Center for Public Health Genomics, University of Virginia School of Medicine
- Mike A Nalls
- Laboratory of Neurogenetics
- Matthias Nauck
- DZHK (German Centre for Cardiovascular Research), partner site Greifswald
- Matt J Neville
- Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Headington
- Ilja M Nolte
- Department of Epidemiology, University of Groningen, University Medical Center Groningen
- Ken K Ong
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine
- Lorena Orozco
- Instituto Nacional de Medicina Genómica
- Sandosh Padmanabhan
- Institute of Cardiovascular and Medical Sciences, University of Glasgow
- Gunnar Pálsson
- deCODE genetics/Amgen Inc.
- James S Pankow
- Division of Epidemiology & Community Health, School of Public Health, University of Minnesota
- Cristian Pattaro
- Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck
- Alison Pattie
- Department of Psychology, University of Edinburgh
- Ozren Polasek
- Centre for Global Health, Faculty of Medicine, University of Split
- Neil Poulter
- International Centre for Circulatory Health, Imperial College London
- Peter P Pramstaller
- Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck
- Lluis Quintana-Murci
- Human Evolutionary Genetics Unit, Institut Pasteur
- Katri Räikkönen
- Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, University of Helsinki
- Sarju Ralhan
- Hero Heart Institute and Dyanand Medical College and Hospital
- Dabeeru C Rao
- Division of Biostatistics, Washington University School of Medicine
- Wouter van Rheenen
- Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht University
- Stephen S Rich
- Center for Public Health Genomics, University of Virginia School of Medicine
- Paul M Ridker
- Division of Preventive Medicine, Brigham and Women’s Hospital
- Cornelius A Rietveld
- Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam
- Antonietta Robino
- Institute for Maternal and Child Health - IRCCS Burlo Garofolo
- Frank J A van Rooij
- Department of Epidemiology, Erasmus University Medical Center
- Daniela Ruggiero
- Institute of Genetics and Biophysics A. Buzzati-Traverso - CNR
- Yasaman Saba
- Gottfried Schatz Research Center (for Cell Signaling, Metabolism and Aging), Division of Molecular Biology and Biochemistry, Medical University of Graz
- Charumathi Sabanayagam
- Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
- Maria Sabater-Lleal
- Cardiovascular Medicine Unit, Department of Medicine Solna, Centre for Molecular Medicine, Karolinska Institutet
- Cinzia Felicita Sala
- San Raffaele Research Institute
- Veikko Salomaa
- Department of Public Health Solutions, National Institute for Health and Welfare
- Kevin Sandow
- Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance
- Helena Schmidt
- Gottfried Schatz Research Center (for Cell Signaling, Metabolism and Aging), Division of Molecular Biology and Biochemistry, Medical University of Graz
- Laura J Scott
- Department of Biostatistics, and Center for Statistical Genetics, University of Michigan
- William R Scott
- Department of Epidemiology and Biostatistics, Imperial College London
- Bahareh Sedaghati-Khayat
- Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences
- Bengt Sennblad
- Cardiovascular Medicine Unit, Department of Medicine Solna, Centre for Molecular Medicine, Karolinska Institutet
- Jessica van Setten
- Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, University of Utrecht, Utrecht
- Peter J Sever
- International Centre for Circulatory Health, Imperial College London
- Wayne H-H Sheu
- School of Medicine, National Defense Medical Center
- Yuan Shi
- Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
- Smeeta Shrestha
- Genomic Research on Complex diseases (GRC Group), CSIR-Centre for Cellular and Molecular Biology
- Sharvari Rahul Shukla
- Diabetes Unit, KEM Hospital and Research Centre
- Jon K Sigurdsson
- deCODE genetics/Amgen Inc.
- Timo Tonis Sikka
- Estonian Genome Center, University of Tartu, University of Tartu
- Jai Rup Singh
- Panjab University
- Blair H Smith
- Division of Population Health Sciences, Ninewells Hospital and Medical School, University of Dundee
- Alena Stančáková
- Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland
- Alice Stanton
- RCSI Molecular & Cellular Therapeutics (MCT), Royal College of Surgeons in Ireland, RCSI Education & Research Centre, Beaumont Hospital
- John M Starr
- Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh
- Lilja Stefansdottir
- deCODE genetics/Amgen Inc.
- Leon Straker
- School of Physiotherapy and Exercise Science, Faculty of Health Sciences, Curtin University
- Patrick Sulem
- deCODE genetics/Amgen Inc.
- Gardar Sveinbjornsson
- deCODE genetics/Amgen Inc.
- Morris A Swertz
- Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands, Groningen
- Adele M Taylor
- Department of Psychology, University of Edinburgh
- Kent D Taylor
- Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance
- Natalie Terzikhan
- Department of Epidemiology, Erasmus University Medical Center
- Yih-Chung Tham
- Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
- Gudmar Thorleifsson
- deCODE genetics/Amgen Inc.
- Unnur Thorsteinsdottir
- deCODE genetics/Amgen Inc.
- Annika Tillander
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
- Russell P Tracy
- Department of Pathology, University of Vermont
- Teresa Tusié-Luna
- Departamento de Medicina Genómica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, UNAM
- Ioanna Tzoulaki
- Department of Epidemiology and Biostatistics, Imperial College London
- Simona Vaccargiu
- Institute of Genetic and Biomedical Research - Support Unity, National Research Council of Italy
- Jagadish Vangipurapu
- Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland
- Jan H Veldink
- Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht University
- Veronique Vitart
- MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh
- Uwe Völker
- Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald
- Eero Vuoksimaa
- Institute for Molecular Medicine Finland (FIMM), University of Helsinki
- Salma M Wakil
- Department of Genetics, King Faisal Specialist Hospital and Research Center
- Melanie Waldenberger
- Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health
- Gurpreet S Wander
- Department of Cardiology, Hero DMC Heart Institute, Dayanand Medical College & Hospital
- Ya Xing Wang
- Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Lab
- Nicholas J Wareham
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine
- Sarah Wild
- Centre for Population Health Sciences, Usher Institute of Population Health and Informatics, University of Edinburgh
- Chittaranjan S Yajnik
- Diabetes Unit, K.E.M. Hospital Research Centre
- Jian-Min Yuan
- Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh
- Lingyao Zeng
- Deutsches Herzzentrum München, Klinik für Herz- und Kreislauferkrankungen, Technische Universität München
- Liang Zhang
- Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
- Jie Zhou
- Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health
- Najaf Amin
- Department of Epidemiology, Erasmus University Medical Center
- Folkert W Asselbergs
- Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, University of Utrecht, Utrecht
- Stephan J L Bakker
- Department of Internal Medicine, University Medical Center Groningen, University of Groningen
- Diane M Becker
- Department of Medicine, GeneSTAR Research Program, Johns Hopkins University School of Medicine
- Benjamin Lehne
- Department of Epidemiology and Biostatistics, Imperial College London
- David A Bennett
- Rush Alzheimer’s Disease Center, Rush University Medical Center
- Leonard H van den Berg
- Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht University
- Sonja I Berndt
- Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health
- Dwaipayan Bharadwaj
- Systems Genomics Laboratory, School of Biotechnology, Jawaharlal Nehru University
- Lawrence F Bielak
- Department of Epidemiology, School of Public Health, University of Michigan
- Murielle Bochud
- Center for Primary Care and Public Health (Unisanté), University of Lausanne
- Mike Boehnke
- Department of Biostatistics, and Center for Statistical Genetics, University of Michigan
- Claude Bouchard
- Pennington Biomedical Research Center
- Jonathan P Bradfield
- Center for Applied Genomics, Division of Human Genetics, Children’s Hospital of Philadelphia
- Jennifer A Brody
- Cardiovascular Health Research Unit, Department of Medicine, University of Washington
- Archie Campbell
- Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh
- Shai Carmi
- Braun School of Public Health, Hebrew University-Hadassah Medical Center
- Mark J Caulfield
- NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London
- David Cesarini
- Center for Experimental Social Science, Department of Economics, New York University, New York
- John C Chambers
- Department of Epidemiology and Biostatistics, Imperial College London
- Giriraj Ratan Chandak
- Genomic Research on Complex diseases (GRC Group), CSIR-Centre for Cellular and Molecular Biology
- Ching-Yu Cheng
- Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
- Marina Ciullo
- Institute of Genetics and Biophysics A. Buzzati-Traverso - CNR
- Marilyn Cornelis
- Department of Preventive Medicine, Northwestern University Feinberg School of Medicine
- Daniele Cusi
- Department of Health Sciences, University of Milano
- George Davey Smith
- MRC Integrative Epidemiology Unit at the University of Bristol
- Ian J Deary
- Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh
- Rajkumar Dorajoo
- Human Genetics, Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore
- Cornelia M van Duijn
- Nuffield Department of Population Health, University of Oxford
- David Ellinghaus
- Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel
- Jeanette Erdmann
- Institute for Cardiogenetics, University of Lübeck
- Johan G Eriksson
- Department of General Practice and Primary health Care, University of Helsinki
- Evangelos Evangelou
- Department of Epidemiology and Biostatistics, Imperial College London
- Michele K Evans
- Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health
- Jessica D Faul
- Survey Research Center, Institute for Social Research, University of Michigan
- Bjarke Feenstra
- Department of Epidemiology Research, Statens Serum Institut
- Mary Feitosa
- Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine
- Sylvain Foisy
- Montreal Heart Institute
- Andre Franke
- Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel
- Yechiel Friedlander
- Braun School of Public Health, Hebrew University-Hadassah Medical Center
- Paolo Gasparini
- Department of Medicine, Surgery and Health Sciences, University of Trieste
- Christian Gieger
- Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health
- Clicerio Gonzalez
- Centro de Estudios en Diabetes, Unidad de Investigacion en Diabetes y Riesgo Cardiovascular, Centro de Investigacion en Salud Poblacional, Instituto Nacional de Salud Publica
- Philippe Goyette
- Montreal Heart Institute
- Struan F A Grant
- Department of Genetics, Perelman School of Medicine, University of Pennsylvania
- Lyn R Griffiths
- Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology
- Leif Groop
- Finnish Institute for Molecular Medicine, University of Helsinki
- Vilmundur Gudnason
- Icelandic Heart Association
- Ulf Gyllensten
- Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University
- Hakon Hakonarson
- Center for Applied Genomics, Division of Human Genetics, Children’s Hospital of Philadelphia
- Anders Hamsten
- Cardiovascular Medicine Unit, Department of Medicine Solna, Centre for Molecular Medicine
- Pim van der Harst
- University of Groningen, University Medical Center Groningen, Department of Cardiology, Ther Netherlands
- Chew-Kiat Heng
- Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore
- Andrew A Hicks
- Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck
- Hagit Hochner
- Braun School of Public Health, Hebrew University-Hadassah Medical Center
- Heikki Huikuri
- Research Unit of Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital
- Steven C Hunt
- Department of Genetic Medicine, Weill Cornell Medicine Qatar
- Vincent W V Jaddoe
- Department of Epidemiology, Erasmus University Medical Center
- Philip L De Jager
- Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center
- Magnus Johannesson
- Department of Economics, Stockholm School of Economics
- Åsa Johansson
- Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University
- Jost B Jonas
- Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Lab
- J Wouter Jukema
- Department of Cardiology, Leiden University Medical Center
- Juhani Junttila
- Research Unit of Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital
- Jaakko Kaprio
- Finnish Institute for Molecular Medicine, University of Helsinki
- Sharon L. R. Kardia
- Department of Epidemiology, School of Public Health, University of Michigan
- Fredrik Karpe
- Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Headington
- Meena Kumari
- Institute for Social and Economic Research, University of Essex
- Markku Laakso
- Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland
- Sander W van der Laan
- Laboratory of Clinical Chemistry and Hematology, Division Laboratories and Pharmacy, University Medical Center Utrecht, University of Utrecht
- Jari Lahti
- Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, University of Helsinki
- Matthias Laudes
- University Hospital Schleswig-Holstein (UKSH)
- Rodney A Lea
- Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology
- Wolfgang Lieb
- Institute of Epidemiology and PopGen Biobank, University of Kiel
- Thomas Lumley
- Department of Statistics, University of Auckland
- Nicholas G Martin
- QIMR Berghofer Institute of Medical Research
- Winfried März
- Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Heidelberg University
- Giuseppe Matullo
- Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences, University of Turin, Italy
- Mark I McCarthy
- Wellcome Centre for Human Genetics, University of Oxford
- Sarah E Medland
- QIMR Berghofer Institute of Medical Research
- Tony R Merriman
- Department of Biochemistry, University of Otago
- Andres Metspalu
- Estonian Genome Center, University of Tartu, University of Tartu
- Brian F Meyer
- Department of Genetics, King Faisal Specialist Hospital and Research Centre
- Karen L Mohlke
- Department of Genetics, University of North Carolina
- Grant W Montgomery
- QIMR Berghofer Institute of Medical Research
- Dennis Mook-Kanamori
- Department of Clinical Epidemiology, Leiden University Medical Center
- Patricia B Munroe
- NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London
- Kari E North
- Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina
- Dale R Nyholt
- QIMR Berghofer Institute of Medical Research
- Jeffery R O’connell
- Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland, School of Medicine
- Carole Ober
- Department of Human Genetics, University of Chicago
- Albertine J Oldehinkel
- Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center Groningen
- Walter Palmas
- Department of Medicine, Columbia University Medical Center
- Colin Palmer
- Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, The School of Medicine, University of Dundee
- Gerard G Pasterkamp
- Laboratory of Clinical Chemistry and Hematology, Division Laboratories and Pharmacy, University Medical Center Utrecht, University of Utrecht, Utrecht
- Etienne Patin
- Human Evolutionary Genetics Unit, Institut Pasteur
- Craig E Pennell
- School of Medicine and Public Health, Faculty of Medicine and Health, The University of Newcastle
- Louis Perusse
- Department of kinesiology, Laval University
- Patricia A Peyser
- Department of Epidemiology, School of Public Health, University of Michigan
- Mario Pirastu
- Institute of Genetic and Biomedical Research - Support Unity, National Research Council of Italy
- Tinca J. C. Polderman
- Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam
- David J Porteous
- Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh
- Danielle Posthuma
- Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam
- Bruce M Psaty
- Cardiovascular Health Research Unit, Departments of Epidemiology, Medicine and Health Services, University of Washington
- John D Rioux
- Montreal Heart Institute
- Fernando Rivadeneira
- Department of Internal Medicine, Erasmus University Medical Center
- Charles Rotimi
- Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health
- Jerome I Rotter
- Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance
- Igor Rudan
- Centre for Global Health Research, Usher Institute, University of Edinburgh
- Hester M Den Ruijter
- Laboratory of Experimental Cardiology, Division Heart & Lungs, University Medical Center Utrecht, University of Utrecht, Utrecht
- Dharambir K Sanghera
- Department of Pediatrics, College of Medicine, University of Oklahoma Health Sciences Center
- Naveed Sattar
- Institute of Cardiovascular and Medical Sciences, University of Glasgow
- Reinhold Schmidt
- Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz
- Matthias B Schulze
- Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke
- Heribert Schunkert
- Deutsches Herzzentrum München, Klinik für Herz- und Kreislauferkrankungen, Technische Universität München
- Robert A Scott
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine
- Alan R Shuldiner
- Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland, School of Medicine
- Xueling Sim
- Saw Swee Hock School of Public Health, National University of Singapore, Singapore
- Neil Small
- Faculty of Health Studies, University of Bradford
- Jennifer A Smith
- Department of Epidemiology, School of Public Health, University of Michigan
- Nona Sotoodehnia
- Cardiovascular Health Research Unit, Division of Cardiology, University of Washington
- E-Shyong Tai
- Saw Swee Hock School of Public Health, National University of Singapore, Singapore
- Alexander Teumer
- DZHK (German Centre for Cardiovascular Research), partner site Greifswald
- Nicholas J Timpson
- MRC Integrative Epidemiology Unit at the University of Bristol
- Daniela Toniolo
- San Raffaele Research Institute
- David-Alexandre Tregouet
- INSERM UMR_S 1166, Sorbonne Universités
- Tiinamaija Tuomi
- Institute for Molecular Medicine Finland, University of Helsinki
- Peter Vollenweider
- Department of Medicine, Internal Medicine, Lausanne University Hospital
- Carol A Wang
- School of Medicine and Public Health, Faculty of Medicine and Health, The University of Newcastle
- David R Weir
- Survey Research Center, Institute for Social Research, University of Michigan
- John B Whitfield
- QIMR Berghofer Institute of Medical Research
- Cisca Wijmenga
- Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands, Groningen
- Tien-Yin Wong
- Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
- John Wright
- Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Trust
- Jingyun Yang
- Rush Alzheimer’s Disease Center, Rush University Medical Center
- Lei Yu
- Rush Alzheimer’s Disease Center, Rush University Medical Center
- Babette S Zemel
- Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania
- Alan B Zonderman
- Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health
- Markus Perola
- Unit of Genomics and Biomarkers, National Institute for Health and Welfare
- Patrik K. E. Magnusson
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
- André G Uitterlinden
- Department of Internal Medicine, Erasmus University Medical Center
- Jaspal S Kooner
- Department of Cardiology, Ealing Hospital, Middlesex
- Daniel I Chasman
- Division of Preventive Medicine, Brigham and Women’s Hospital
- Ruth J. F. Loos
- The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai
- Nora Franceschini
- Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina
- Lude Franke
- Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands, Groningen
- Chris S Haley
- MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh
- Caroline Hayward
- MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh
- Robin G Walters
- Nuffield Department of Population Health, University of Oxford
- John R. B. Perry
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine
- Tōnu Esko
- Estonian Genome Center, University of Tartu, University of Tartu
- Agnar Helgason
- deCODE genetics/Amgen Inc.
- Kari Stefansson
- deCODE genetics/Amgen Inc.
- Peter K Joshi
- Centre for Global Health Research, Usher Institute, University of Edinburgh
- Michiaki Kubo
- Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences
- James F Wilson
- Centre for Global Health Research, Usher Institute, University of Edinburgh
- DOI
- https://doi.org/10.1038/s41467-019-12283-6
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 17
Abstract
Inbreeding depression has been observed in many different species, but in humans a systematic analysis has been difficult so far. Here, analysing more than 1.3 million individuals, the authors show that a genomic inbreeding coefficient (FROH) is associated with disadvantageous outcomes in 32 out of 100 traits tested.
