Case Report: Epstein–Barr Virus Encephalitis Complicated With Brain Stem Hemorrhage in an Immune-Competent Adult

Lingtong Huang; Xuan Zhang; Xueling Fang

doi:10.3389/fimmu.2021.618830

Frontiers in Immunology (Feb 2021)

Case Report: Epstein–Barr Virus Encephalitis Complicated With Brain Stem Hemorrhage in an Immune-Competent Adult

Lingtong Huang,
Xuan Zhang,
Xueling Fang

Affiliations

Lingtong Huang: Department of Critical Care Units, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
Xuan Zhang: Department of Infectious Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
Xueling Fang: Department of Critical Care Units, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China

DOI: https://doi.org/10.3389/fimmu.2021.618830
Journal volume & issue: Vol. 12

Abstract

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Encephalitis caused by Epstein-Barr virus infection is uncommon, but most patients have a good outcome after symptomatic treatment. The infiltration of mononuclear cells in blood vessels and necrosis resulting from the immune response to Epstein-Barr virus infection in a very small number of patients seem to be the main cause of death. We describe a fatal case of Epstein-Barr virus encephalitis diagnosed by next-generation sequencing in an immune-competent adult but progressed to brainstem hemorrhage.

Published in Frontiers in Immunology

ISSN: 1664-3224 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Immunologic diseases. Allergy
Website: http://journal.frontiersin.org/journal/immunology

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Abstract

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