Antimicrobial susceptibility and molecular characterization for some virulence factors of Proteus Mirabilis isolated from patients in Al-Qadisiyah Province/ Iraq

Abstract

Total of 64 Samples clinical isolates were collected from various sources included urine, ear external swab, wounds swab, burns swab, high cervical and endometrium cervical swab, which was taken from (in-patients) and (out-patients) in Maternal, and General Teaching Hospital in AL-Diwaniya city during the period from 1/3/2015 till 30/9/2015. The resistance of bacterial isolates to 12 different antibiotics was tested and isolates showed different resistance to anti-βata Lactam including penicillin and Amoxicillin/ Clavulanic acid by (100%), cefotaxime by (86%), and Cephalexin by (90.62%), Imipenem by (18.75%), and Meropenem by (15.62%). Some of the virulence factors have been studied genetically (20 isolates), in terms of the genetic aspect, five genes were obtained for virulence factors and at varying rates, as the urease enzyme ureC, fimbriae formation mrpA, flagella flaA, hemolysin enzyme hpmA and biofilm formation luxS (60, 40,100, 45, 55) % , respectively.