European Journal of Case Reports in Internal Medicine (Sep 2022)

Takotsubo Cardiomyopathy After Cocaine Intoxication: A Case Report

  • Aditya Patel,
  • Noreen Mirza,
  • Ruhma Ali,
  • Mohammad Nabil Rayad,
  • Asrar Ahmad,
  • Ahsan Khan

DOI
https://doi.org/10.12890/2022_003457

Abstract

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Introduction: Cocaine is a highly addictive substance that stimulates the sympathetic nervous system and cardiovascular system. A multitude of adverse cardiovascular events are associated with cocaine use including arrhythmia, congestive heart failure, coronary artery spasm and myocarditis. Case Report: We present a rare case of Takotsubo cardiomyopathy after recent use of cocaine in a female without any other identifiable risk factor. Discussion: Takotsubo cardiomyopathy (TCM) is a reversible cause of cardiomyopathy characterized by transient decrease in ejection fraction. Cocaine is a sympathomimetic that causes catecholamine surge and a variety of cardiovascular abnormalities. The association of cocaine use with Takotsubo cardiomyopathy is a rare occurrence, however the prognosis is generally good if diagnosis is made promptly. Conclusion: Physician vigilance is required to diagnose this rare cause of cardiomyopathy and reduce morbidity and mortality.

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