Frontiers in Immunology (May 2024)

Anti-NMDAR encephalitis in a child with long impaired consciousness and persistent antibodies: a case report and mini review

  • Wenhao Zhang,
  • Wenjia Cao,
  • Wenhan Tao,
  • Yufei Wang,
  • Chenchen Tangzhu,
  • Qinru Shen,
  • Xulai Shi

DOI
https://doi.org/10.3389/fimmu.2024.1402523
Journal volume & issue
Vol. 15

Abstract

Read online

We described a challenging case of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in a young girl. Despite enduring months of reduced consciousness with ongoing antibody presence, she ultimately exhibited remarkable improvement within a 5-year follow-up period. Additionally, we conducted a concise review of relevant literature on anti-NMDAR encephalitis, with a specific focus on anti-NMDAR antibodies. Our findings enhance the clinical comprehension of anti-NMDAR encephalitis and offer valuable insights to clinicians for its management.

Keywords