PLoS ONE (Jan 2023)

Factors associated with higher hemoglobin A1c and type 2 diabetes-related costs: Secondary data analysis of adults 18 to 64 in Texas with commercial insurance.

  • Marcia G Ory,
  • Gang Han,
  • Sagar N Jani,
  • Lixian Zhong,
  • Elena Andreyeva,
  • Keri Carpenter,
  • Samuel D Towne,
  • Veronica Averhart Preston,
  • Matthew Lee Smith

DOI
https://doi.org/10.1371/journal.pone.0289491
Journal volume & issue
Vol. 18, no. 9
p. e0289491

Abstract

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ObjectiveThis study will identify factors associated with higher hemoglobin A1c (A1c) values and diabetes-related costs among commercially insured adults in Texas diagnosed with type 2 diabetes.Research design and methodsThis secondary data analysis was based on claims data from commercially insured individuals 18-64 years of age residing in Texas with diagnosed type 2 diabetes during the 2018-2019 study period. The final analysis sample after all the exclusions consisted of 34,992 individuals. Measures included hemoglobin A1c, diabetes-related costs, Charlson Comorbidity Index, diabetes-related complications, rurality and other socioeconomic characteristics. Longitudinal A1c measurements were modeled using age, sex, rurality, comorbidity, and diabetes-related complications in generalized linear longitudinal regression models adjusting the observation time, which was one of the 8 quarters in 2018 and 2019. The diabetes-related costs were similarly modeled in both univariable and multivariable generalized linear longitudinal regression models adjusting the observation time by calendar quarters and covariates.ResultsThe median A1c value was 7, and the median quarterly diabetes-related cost was $120. A positive statistically significant relationship (p = ConclusionThe study adds updated analyses of the interrelationships among demographic and geographic factors, clinical indicators, and health-related costs, reinforcing the role of higher A1c values and complications as diabetes-related cost drivers.