Contemporary Clinical Trials Communications (Mar 2021)
Managing work flow in high enrolling trials: The development and implementation of a sampling strategy in the PREPARE trial
- David Pogorzelski,
- Uyen Nguyen,
- Paula McKay,
- Lehana Thabane,
- Megan Camara,
- Lolita Ramsey,
- Rachel Seymour,
- J. Brett Goodman,
- Sheketha McGee,
- Joanne Fraifogl,
- Andrea Hudgins,
- Stephanie L. Tanner,
- Mohit Bhandari,
- Gerard P. Slobogean,
- Sheila Sprague,
- Gerard P. Slobogean,
- Sheila Sprague,
- Jeffrey Wells,
- Mohit Bhandari,
- Gerard P. Slobogean,
- Mohit Bhandari,
- Sheila Sprague,
- Jean-Claude D'Alleyrand,
- Anthony D. Harris,
- Daniel C. Mullins,
- Lehana Thabane,
- Jeffrey Wells,
- Amber Wood,
- Gregory J. Della Rocca,
- Anthony D. Harris,
- Joan Hebden,
- Kyle J. Jeray,
- Lucas Marchand,
- Lyndsay M. O'Hara,
- Robert Zura,
- Michael J. Gardner,
- Jenna Blasman,
- Jonah Davies,
- Stephen Liang,
- Monica Taljaard,
- P.J. Devereaux,
- Gordon H. Guyatt,
- Lehana Thabane,
- Diane Heels-Ansdell,
- Debra Marvel,
- Jana Palmer,
- Jeffrey Wells,
- Jeff Friedrich,
- Daniel C. Mullins,
- Nathan N. O'Hara,
- Ms. Frances Grissom,
- Gregory J. Della Rocca,
- I. Leah Gitajn,
- Kyle J. Jeray,
- Saam Morshed,
- Robert V. O'Toole,
- Bradley A. Petrisor,
- Megan Camara,
- Franca Mossuto,
- Anthony D. Harris,
- Manjari G. Joshi,
- Jean-Claude D'Alleyrand,
- Justin Fowler,
- Jessica Rivera,
- Max Talbot,
- Sheila Sprague,
- Mohit Bhandari,
- Shannon Dodds,
- Alisha Garibaldi,
- Silvia Li,
- Uyen Nguyen,
- David Pogorzelski,
- Alejandra Rojas,
- Taryn Scott,
- Gina Del Fabbro,
- Olivia Paige Szasz,
- Diane Heels-Ansdell,
- Paula McKay,
- Gerard P. Slobogean,
- Nathan N. O'Hara,
- Andrea Howe,
- Joshua Rudnicki,
- Haley Demyanovich,
- Kelly Little,
- C. Daniel Mullins,
- Michelle Medeiros,
- Eric Kettering,
- Diamond Hale,
- Robert V. O'Toole,
- Jean-Claude D'Alleyrand,
- Andrew Eglseder,
- Aaron Johnson,
- Christopher Langhammer,
- Christopher Lebrun,
- Theodore Manson,
- Jason Nascone,
- Ebrahim Paryavi,
- Raymond Pensy,
- Andrew Pollak,
- Marcus Sciadini,
- Gerard P. Slobogean,
- Yasmin Degani,
- Haley K. Demyanovich,
- Andrea Howe,
- Nathan N. O'Hara,
- Katherine Joseph,
- Joshua Rudnicki,
- Megan Camara,
- Brad A. Petrisor,
- Herman Johal,
- Bill Ristevski,
- Dale Williams,
- Matthew Denkers,
- Krishan Rajaratnam,
- Jamal Al-Asiri,
- Jordan Leonard,
- Francesc A. Marcano-Fernández,
- Jodi Gallant,
- Federico Persico,
- Marko Gjorgjievski,
- Annie George,
- Roman M. Natoli,
- Greg E. Gaski,
- Todd O. McKinley,
- Walter W. Virkus,
- Anthony T. Sorkin,
- Jan P. Szatkowski,
- Joseph R. Baele,
- Brian H. Mullis,
- Lauren C. Hill,
- Andrea Hudgins,
- Patrick Osborn,
- Justin Fowler,
- Sarah Pierrie,
- Eric Martinez,
- Joseph Kimmel,
- Kyle J. Jeray,
- John D. Adams,
- Michael L. Beckish,
- Christopher C. Bray,
- Timothy R. Brown,
- Andrew W. Cross,
- Timothy Dew,
- Gregory K. Faucher,
- Richard W. Gurich, Jr.,
- David E. Lazarus,
- S. John Millon,
- M. Jason Palmer,
- Scott E. Porter,
- Thomas M. Schaller,
- Michael S. Sridhar,
- John L. Sanders,
- L. Edwin Rudisill, Jr.,
- Michael J. Garitty,
- Andrew S. Poole,
- Michael L. Sims,
- Clark M. Walker,
- Robert M. Carlisle, II,
- Erin Adams Hofer,
- Brandon S. Huggins,
- Michael D. Hunter,
- William A. Marshall,
- Shea Bielby Ray,
- Cory D. Smith,
- Kyle M. Altman,
- Julia C. Bedard,
- Markus F. Loeffler,
- Erin R. Pichiotino,
- Austin A. Cole,
- Ethan J. Maltz,
- Wesley Parker,
- T. Bennett Ramsey,
- Alex Burnikel,
- Michael Colello,
- Russell Stewart,
- Jeremy Wise,
- M. Christian Moody,
- Stephanie L. Tanner,
- Rebecca G. Snider,
- Christine E. Townsend,
- Kayla H. Pham,
- Abigail Martin,
- Emily Robertson,
- Saam Morshed,
- Theodore Miclau,
- Utku Kandemir,
- Meir Marmor,
- Amir Matityahu,
- R. Trigg McClellan,
- Eric Meinberg,
- David Shearer,
- Paul Toogood,
- Anthony Ding,
- Erin Donohue,
- Tigist Belaye,
- Eleni Berhaneselase,
- Alexandra Paul,
- Kartik Garg,
- Joshua L. Gary,
- Stephen J. Warner,
- John W. Munz,
- Andrew M. Choo,
- Timothy S. Achor,
- Milton L. “Chip” Routt,
- Mayank Rao,
- Guillermo Pechero,
- Adam Miller,
- Jennifer E. Hagen,
- Matthew Patrick,
- Richard Vlasak,
- Thomas Krupko,
- Kalia Sadasivan,
- Chris Koenig,
- Daniel Bailey,
- Daniel Wentworth,
- Chi Van,
- Justin Schwartz,
- Niloofar Dehghan,
- Clifford B. Jones,
- J Tracy Watson,
- Michael McKee,
- Ammar Karim,
- Michael Talerico,
- Debra L. Sietsema,
- Alyse Williams,
- Tayler Dykes,
- William T. Obremskey,
- Amir Alex Jahangir,
- Manish Sethi,
- Robert Boyce,
- Daniel J. Stinner,
- Phillip Mitchell,
- Karen Trochez,
- Andres Rodriguez,
- Vamshi Gajari,
- Elsa Rodriguez,
- Charles Pritchett,
- Christina Boulton,
- Jason Lowe,
- Jason Wild,
- John T. Ruth,
- Michel Taylor,
- Andrea Seach,
- Sabina Saeed,
- Hunter Culbert,
- Alejandro Cruz,
- Thomas Knapp,
- Colin Hurkett,
- Maya Lowney,
- Michael Prayson,
- Indresh Venkatarayappa,
- Brandon Horne,
- Jennifer Jerele,
- Linda Clark,
- Francesc Marcano-Fernández,
- Montsant Jornet-Gibert,
- Laia Martínez-Carreres,
- David Martí-Garín,
- Jorge Serrano-Sanz,
- Joel Sánchez-Fernández,
- Matsuyama Sanz-Molero,
- Alejandro Carballo,
- Xavier Pelfort,
- Francesc Acerboni-Flores,
- Anna Alavedra-Massana,
- Neus Anglada-Torres,
- Alexandre Berenguer,
- Jaume Cámara-Cabrera,
- Ariadna Caparros-García,
- Ferran Fillat-Gomà,
- Ruben Fuentes-López,
- Ramona Garcia-Rodriguez,
- Nuria Gimeno-Calavia,
- Guillem Graells-Alonso,
- Marta Martínez-Álvarez,
- Patricia Martínez-Grau,
- Raúl Pellejero-García,
- Ona Ràfols-Perramon,
- Juan Manuel Peñalver,
- Mònica Salomó Domènech,
- Albert Soler-Cano,
- Aldo Velasco-Barrera,
- Christian Yela-Verdú,
- Mercedes Bueno-Ruiz,
- Estrella Sánchez-Palomino,
- Ernesto Guerra,
- Yaiza García,
- Nicholas M. Romeo,
- Heather A. Vallier,
- Mary A. Breslin,
- Joanne Fraifogl,
- Eleanor S. Wilson,
- Leanne K. Wadenpfuhl,
- Paul G. Halliday,
- Darius G. Viskontas,
- Kelly L. Apostle,
- Dory S. Boyer,
- Farhad O. Moola,
- Bertrand H. Perey,
- Trevor B. Stone,
- H. Michael Lemke,
- Mauri Zomar,
- Ella Spicer,
- Chen “Brenda” Fan,
- Kyrsten Payne,
- Kevin Phelps,
- Michael Bosse,
- Madhav Karunakar,
- Laurence Kempton,
- Stephen Sims,
- Joseph Hsu,
- Rachel Seymour,
- Christine Churchill,
- Claire Bartel,
- Robert Miles Mayberry,
- Maggie Brownrigg,
- Cara Girardi,
- Ada Mayfield,
- Robert A. Hymes,
- Cary C. Schwartzbach,
- Jeff E. Schulman,
- A. Stephen Malekzadeh,
- Michael A. Holzman,
- Lolita Ramsey,
- James S. Ahn,
- Farhanaz Panjshiri,
- Sharmistha Das,
- Antoinisha D. English,
- Sharon M. Haaser,
- Jaslynn A.N. Cuff,
- Holly Pilson,
- Eben A. Carroll,
- Jason J. Halvorson,
- Sharon Babcock,
- J. Brett Goodman,
- Martha B. Holden,
- Debra Bullard,
- Wendy Williams,
- Thomas F. Higgins,
- Justin M. Haller,
- David L. Rothberg,
- Ashley Neese,
- Mark Russell,
- I. Leah Gitajn,
- Marcus Coe,
- Kevin Dwyer,
- Devin S. Mullin,
- Clifford A. Reilly,
- Peter DePalo,
- Amy E. Hall,
- Marilyn Heng,
- Mitchel B. Harris,
- R. Malcolm Smith,
- David W. Lhowe,
- John G. Esposito,
- Mira Bansal,
- Patrick F. Bergin,
- George V. Russell,
- Matthew L. Graves,
- John Morellato,
- Heather K. Champion,
- Leslie N. Johnson,
- Sheketha L. McGee,
- Eldrin L. Bhanat,
- Samir Mehta,
- Derek Donegan,
- Jaimo Ahn,
- Annamarie Horan,
- Mary Dooley,
- Ashley Kuczinski,
- Ashley Iwu,
- David Potter,
- Robert VanDemark, III,
- Branden Pfaff,
- Troy Hollinsworth,
- Michael J. Weaver,
- Arvind G. von Keudell,
- Michael F. McTague,
- Elizabeth M. Allen,
- Todd Jaeblon,
- Robert Beer,
- Haley K. Demyanovich,
- Mark J. Gage,
- Rachel M. Reilly,
- Cindy Sparrow
Affiliations
- David Pogorzelski
- Department of Surgery, McMaster University, 293 Wellington St. N., Suite 110, Hamilton, ON, Canada
- Uyen Nguyen
- Department of Surgery, McMaster University, 293 Wellington St. N., Suite 110, Hamilton, ON, Canada
- Paula McKay
- Department of Surgery, McMaster University, 293 Wellington St. N., Suite 110, Hamilton, ON, Canada
- Lehana Thabane
- Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main St. W., Hamilton, ON, Canada
- Megan Camara
- R Adams Cowley Shock Trauma Center, 22 S Greene St., Baltimore, MD, United States
- Lolita Ramsey
- Inova Fairfax Medical Campus, 3300 Gallows Rd., Falls Church, VA, United States
- Rachel Seymour
- Department of Orthopaedic Surgery, Atrium Health Musculoskeletal Institute, NC, United States
- J. Brett Goodman
- Department of Orthopaedic Surgery, Wake Forest Baptist Medical Center, 1 Medical Center Blvd., Winston-Salem, NC, United States
- Sheketha McGee
- University of Mississippi Medical Center, 2500 N State St., Jackson, MS, United States
- Joanne Fraifogl
- The MetroHealth System, 2500 Metrohealth Dr., Cleveland, OH, United States
- Andrea Hudgins
- IU School of Medicine, 340 W 10th St., Indianapolis, IN, United States
- Stephanie L. Tanner
- Department of Orthopaedic Surgery, Prisma Health – Upstate, 701 Grove Rd., Greenville, SC, United States
- Mohit Bhandari
- Department of Surgery, McMaster University, 293 Wellington St. N., Suite 110, Hamilton, ON, Canada; Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main St. W., Hamilton, ON, Canada
- Gerard P. Slobogean
- University of Maryland School of Medicine, 655 W Baltimore St. S., Baltimore, MD, United States
- Sheila Sprague
- Department of Surgery, McMaster University, 293 Wellington St. N., Suite 110, Hamilton, ON, Canada; Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main St. W., Hamilton, ON, Canada; Corresponding author. Division of Orthopaedic Surgery, Department of Surgery, McMaster University, 293 Wellington Street North, Suite 110, Hamilton, Ontario, L8L 8E7, Canada.
- Gerard P. Slobogean
- University of Maryland School of Medicine, Baltimore, MD, United States
- Sheila Sprague
- McMaster University, Hamilton, ON, Canada
- Jeffrey Wells
- Trauma Survivors Network, Falls Church, VA, United States
- Mohit Bhandari
- McMaster University, Hamilton, ON, Canada
- Gerard P. Slobogean
- University of Maryland School of Medicine, Baltimore, MD, United States
- Mohit Bhandari
- McMaster University, Hamilton, ON, Canada
- Sheila Sprague
- McMaster University, Hamilton, ON, Canada
- Jean-Claude D'Alleyrand
- Walter Reed National Military Medical Center, Bethesda, MD, United States
- Anthony D. Harris
- University of Maryland School of Medicine, Baltimore, MD, United States
- Daniel C. Mullins
- University of Maryland, Baltimore, MD, United States
- Lehana Thabane
- McMaster University, Hamilton, ON, Canada
- Jeffrey Wells
- Trauma Survivors Network, Falls Church, VA, United States
- Amber Wood
- Association of periOperative Registered Nurses, Denver, CO, United States
- Gregory J. Della Rocca
- University of Missouri, Columbia, MO, United States
- Anthony D. Harris
- University of Maryland School of Medicine, Baltimore, MD, United States
- Joan Hebden
- University of Maryland, Baltimore, MD, United States
- Kyle J. Jeray
- Greenville Health System, Greenville, SC, United States
- Lucas Marchand
- University of Maryland, Baltimore, MD, United States
- Lyndsay M. O'Hara
- University of Maryland School of Medicine, Baltimore, MD, United States
- Robert Zura
- LSU Health, New Orleans, LA, United States
- Michael J. Gardner
- Stanford University School of Medicine, Palo Alto, CA, United States
- Jenna Blasman
- Kitchener, ON, Canada
- Jonah Davies
- University of Washington, Seattle, WA, United States
- Stephen Liang
- Washington University, St. Louis, MO, United States
- Monica Taljaard
- Ottawa Hospital Research Institute, Ottawa, ON, Canada
- P.J. Devereaux
- McMaster University, Hamilton, ON, Canada
- Gordon H. Guyatt
- McMaster University, Hamilton, ON, Canada
- Lehana Thabane
- McMaster University, Hamilton, ON, Canada
- Diane Heels-Ansdell
- McMaster University, Hamilton, ON, Canada
- Debra Marvel
- Baltimore, MD, United States
- Jana Palmer
- Baltimore, MD, United States
- Jeffrey Wells
- Trauma Survivors Network, Falls Church, VA, United States
- Jeff Friedrich
- Slate Magazine, Washington, DC, United States
- Daniel C. Mullins
- University of Maryland, Baltimore, MD, United States
- Nathan N. O'Hara
- University of Maryland School of Medicine, Baltimore, MD, United States
- Ms. Frances Grissom
- Trauma Survivor Network, Baltimore, MD, United States
- Gregory J. Della Rocca
- University of Missouri, Columbia, MO, United States
- I. Leah Gitajn
- Dartmouth University, Hanover, NH, United States
- Kyle J. Jeray
- Greenville Health System, Greenville, SC, United States
- Saam Morshed
- San Francisco General Hospital, San Francisco, CA, United States
- Robert V. O'Toole
- University of Maryland School of Medicine, Baltimore, MD, United States
- Bradley A. Petrisor
- Hamilton Health Science, Hamilton, ON, Canada
- Megan Camara
- R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Franca Mossuto
- Hamilton Health Science, Hamilton, ON, Canada
- Anthony D. Harris
- University of Maryland School of Medicine, Baltimore, MD, United States
- Manjari G. Joshi
- University of Maryland School of Medicine, Baltimore, MD, United States
- Jean-Claude D'Alleyrand
- Walter Reed National Military Medical Center, Bethesda, MD, United States
- Justin Fowler
- United States Army, United States
- Jessica Rivera
- San Antonio Military Medical Center, San Antonio, TX, United States
- Max Talbot
- Canadian Armed Forces, Montreal, QC, Canada
- Sheila Sprague
- McMaster University Methods Center, Hamilton, ON, Canada
- Mohit Bhandari
- McMaster University Methods Center, Hamilton, ON, Canada
- Shannon Dodds
- McMaster University Methods Center, Hamilton, ON, Canada
- Alisha Garibaldi
- McMaster University Methods Center, Hamilton, ON, Canada
- Silvia Li
- McMaster University Methods Center, Hamilton, ON, Canada
- Uyen Nguyen
- McMaster University Methods Center, Hamilton, ON, Canada
- David Pogorzelski
- McMaster University Methods Center, Hamilton, ON, Canada
- Alejandra Rojas
- McMaster University Methods Center, Hamilton, ON, Canada
- Taryn Scott
- McMaster University Methods Center, Hamilton, ON, Canada
- Gina Del Fabbro
- McMaster University Methods Center, Hamilton, ON, Canada
- Olivia Paige Szasz
- McMaster University Methods Center, Hamilton, ON, Canada
- Diane Heels-Ansdell
- McMaster University Methods Center, Hamilton, ON, Canada
- Paula McKay
- McMaster University Methods Center, Hamilton, ON, Canada
- Gerard P. Slobogean
- University of Maryland School of Medicine Administrative Center, Baltimore, MD, United States
- Nathan N. O'Hara
- University of Maryland School of Medicine Administrative Center, Baltimore, MD, United States
- Andrea Howe
- University of Maryland School of Medicine Administrative Center, Baltimore, MD, United States
- Joshua Rudnicki
- University of Maryland School of Medicine Administrative Center, Baltimore, MD, United States
- Haley Demyanovich
- University of Maryland School of Medicine Administrative Center, Baltimore, MD, United States
- Kelly Little
- University of Maryland School of Medicine Administrative Center, Baltimore, MD, United States
- C. Daniel Mullins
- University of Maryland School of Pharmacy, The PATIENTS Program, Baltimore, MD, United States
- Michelle Medeiros
- University of Maryland School of Pharmacy, The PATIENTS Program, Baltimore, MD, United States
- Eric Kettering
- University of Maryland School of Pharmacy, The PATIENTS Program, Baltimore, MD, United States
- Diamond Hale
- University of Maryland School of Pharmacy, The PATIENTS Program, Baltimore, MD, United States
- Robert V. O'Toole
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Jean-Claude D'Alleyrand
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Andrew Eglseder
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Aaron Johnson
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Christopher Langhammer
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Christopher Lebrun
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Theodore Manson
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Jason Nascone
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Ebrahim Paryavi
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Raymond Pensy
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Andrew Pollak
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Marcus Sciadini
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Gerard P. Slobogean
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Yasmin Degani
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Haley K. Demyanovich
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Andrea Howe
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Nathan N. O'Hara
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Katherine Joseph
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Joshua Rudnicki
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Megan Camara
- University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, MD, United States
- Brad A. Petrisor
- Hamilton Health Sciences – General Site, Hamilton, ON, Canada
- Herman Johal
- Hamilton Health Sciences – General Site, Hamilton, ON, Canada
- Bill Ristevski
- Hamilton Health Sciences – General Site, Hamilton, ON, Canada
- Dale Williams
- Hamilton Health Sciences – General Site, Hamilton, ON, Canada
- Matthew Denkers
- Hamilton Health Sciences – General Site, Hamilton, ON, Canada
- Krishan Rajaratnam
- Hamilton Health Sciences – General Site, Hamilton, ON, Canada
- Jamal Al-Asiri
- Hamilton Health Sciences – General Site, Hamilton, ON, Canada
- Jordan Leonard
- Hamilton Health Sciences – General Site, Hamilton, ON, Canada
- Francesc A. Marcano-Fernández
- Hamilton Health Sciences – General Site, Hamilton, ON, Canada
- Jodi Gallant
- Hamilton Health Sciences – General Site, Hamilton, ON, Canada
- Federico Persico
- Hamilton Health Sciences – General Site, Hamilton, ON, Canada
- Marko Gjorgjievski
- Hamilton Health Sciences – General Site, Hamilton, ON, Canada
- Annie George
- Hamilton Health Sciences – General Site, Hamilton, ON, Canada
- Roman M. Natoli
- IU Health Methodist Hospital, Indianapolis, IN, United States
- Greg E. Gaski
- IU Health Methodist Hospital, Indianapolis, IN, United States
- Todd O. McKinley
- IU Health Methodist Hospital, Indianapolis, IN, United States
- Walter W. Virkus
- IU Health Methodist Hospital, Indianapolis, IN, United States
- Anthony T. Sorkin
- IU Health Methodist Hospital, Indianapolis, IN, United States
- Jan P. Szatkowski
- IU Health Methodist Hospital, Indianapolis, IN, United States
- Joseph R. Baele
- IU Health Methodist Hospital, Indianapolis, IN, United States
- Brian H. Mullis
- IU Health Methodist Hospital, Indianapolis, IN, United States
- Lauren C. Hill
- IU Health Methodist Hospital, Indianapolis, IN, United States
- Andrea Hudgins
- IU Health Methodist Hospital, Indianapolis, IN, United States
- Patrick Osborn
- San Antonio Military Medical Center, San Antonio, TX, United States
- Justin Fowler
- San Antonio Military Medical Center, San Antonio, TX, United States
- Sarah Pierrie
- San Antonio Military Medical Center, San Antonio, TX, United States
- Eric Martinez
- San Antonio Military Medical Center, San Antonio, TX, United States
- Joseph Kimmel
- San Antonio Military Medical Center, San Antonio, TX, United States
- Kyle J. Jeray
- Prisma Health - Upstate, Greenville, SC, United States
- John D. Adams
- Prisma Health - Upstate, Greenville, SC, United States
- Michael L. Beckish
- Prisma Health - Upstate, Greenville, SC, United States
- Christopher C. Bray
- University of California, San Francisco, San Francisco, CA, United States
- Timothy R. Brown
- Prisma Health - Upstate, Greenville, SC, United States
- Andrew W. Cross
- Prisma Health - Upstate, Greenville, SC, United States
- Timothy Dew
- Prisma Health - Upstate, Greenville, SC, United States
- Gregory K. Faucher
- Prisma Health - Upstate, Greenville, SC, United States
- Richard W. Gurich, Jr.
- Prisma Health - Upstate, Greenville, SC, United States
- David E. Lazarus
- Prisma Health - Upstate, Greenville, SC, United States
- S. John Millon
- Prisma Health - Upstate, Greenville, SC, United States
- M. Jason Palmer
- Prisma Health - Upstate, Greenville, SC, United States
- Scott E. Porter
- Prisma Health - Upstate, Greenville, SC, United States
- Thomas M. Schaller
- Prisma Health - Upstate, Greenville, SC, United States
- Michael S. Sridhar
- Prisma Health - Upstate, Greenville, SC, United States
- John L. Sanders
- Prisma Health - Upstate, Greenville, SC, United States
- L. Edwin Rudisill, Jr.
- Prisma Health - Upstate, Greenville, SC, United States
- Michael J. Garitty
- Prisma Health - Upstate, Greenville, SC, United States
- Andrew S. Poole
- Prisma Health - Upstate, Greenville, SC, United States
- Michael L. Sims
- Prisma Health - Upstate, Greenville, SC, United States
- Clark M. Walker
- Prisma Health - Upstate, Greenville, SC, United States
- Robert M. Carlisle, II
- Prisma Health - Upstate, Greenville, SC, United States
- Erin Adams Hofer
- Prisma Health - Upstate, Greenville, SC, United States
- Brandon S. Huggins
- Prisma Health - Upstate, Greenville, SC, United States
- Michael D. Hunter
- Prisma Health - Upstate, Greenville, SC, United States
- William A. Marshall
- Prisma Health - Upstate, Greenville, SC, United States
- Shea Bielby Ray
- Prisma Health - Upstate, Greenville, SC, United States
- Cory D. Smith
- Prisma Health - Upstate, Greenville, SC, United States
- Kyle M. Altman
- Prisma Health - Upstate, Greenville, SC, United States
- Julia C. Bedard
- Prisma Health - Upstate, Greenville, SC, United States
- Markus F. Loeffler
- Prisma Health - Upstate, Greenville, SC, United States
- Erin R. Pichiotino
- Prisma Health - Upstate, Greenville, SC, United States
- Austin A. Cole
- Prisma Health - Upstate, Greenville, SC, United States
- Ethan J. Maltz
- Prisma Health - Upstate, Greenville, SC, United States
- Wesley Parker
- Prisma Health - Upstate, Greenville, SC, United States
- T. Bennett Ramsey
- Prisma Health - Upstate, Greenville, SC, United States
- Alex Burnikel
- Prisma Health - Upstate, Greenville, SC, United States
- Michael Colello
- Prisma Health - Upstate, Greenville, SC, United States
- Russell Stewart
- Prisma Health - Upstate, Greenville, SC, United States
- Jeremy Wise
- Prisma Health - Upstate, Greenville, SC, United States
- M. Christian Moody
- Prisma Health - Upstate, Greenville, SC, United States
- Stephanie L. Tanner
- Prisma Health - Upstate, Greenville, SC, United States
- Rebecca G. Snider
- Prisma Health - Upstate, Greenville, SC, United States
- Christine E. Townsend
- Prisma Health - Upstate, Greenville, SC, United States
- Kayla H. Pham
- Prisma Health - Upstate, Greenville, SC, United States
- Abigail Martin
- Prisma Health - Upstate, Greenville, SC, United States
- Emily Robertson
- Prisma Health - Upstate, Greenville, SC, United States
- Saam Morshed
- University of California, San Francisco, San Francisco, CA, United States
- Theodore Miclau
- University of California, San Francisco, San Francisco, CA, United States
- Utku Kandemir
- University of California, San Francisco, San Francisco, CA, United States
- Meir Marmor
- University of California, San Francisco, San Francisco, CA, United States
- Amir Matityahu
- University of California, San Francisco, San Francisco, CA, United States
- R. Trigg McClellan
- University of California, San Francisco, San Francisco, CA, United States
- Eric Meinberg
- University of California, San Francisco, San Francisco, CA, United States
- David Shearer
- University of California, San Francisco, San Francisco, CA, United States
- Paul Toogood
- University of California, San Francisco, San Francisco, CA, United States
- Anthony Ding
- University of California, San Francisco, San Francisco, CA, United States
- Erin Donohue
- University of California, San Francisco, San Francisco, CA, United States
- Tigist Belaye
- University of California, San Francisco, San Francisco, CA, United States
- Eleni Berhaneselase
- University of California, San Francisco, San Francisco, CA, United States
- Alexandra Paul
- University of California, San Francisco, San Francisco, CA, United States
- Kartik Garg
- University of California, San Francisco, San Francisco, CA, United States
- Joshua L. Gary
- McGovern Medical School at UTHealth Houston, Houston, TX, United States
- Stephen J. Warner
- McGovern Medical School at UTHealth Houston, Houston, TX, United States
- John W. Munz
- McGovern Medical School at UTHealth Houston, Houston, TX, United States
- Andrew M. Choo
- McGovern Medical School at UTHealth Houston, Houston, TX, United States
- Timothy S. Achor
- McGovern Medical School at UTHealth Houston, Houston, TX, United States
- Milton L. “Chip” Routt
- McGovern Medical School at UTHealth Houston, Houston, TX, United States
- Mayank Rao
- McGovern Medical School at UTHealth Houston, Houston, TX, United States
- Guillermo Pechero
- McGovern Medical School at UTHealth Houston, Houston, TX, United States
- Adam Miller
- McGovern Medical School at UTHealth Houston, Houston, TX, United States
- Jennifer E. Hagen
- University of Florida, Gainesville, FL, United States
- Matthew Patrick
- University of Florida, Gainesville, FL, United States
- Richard Vlasak
- University of Florida, Gainesville, FL, United States
- Thomas Krupko
- University of Florida, Gainesville, FL, United States
- Kalia Sadasivan
- University of Florida, Gainesville, FL, United States
- Chris Koenig
- University of Florida, Gainesville, FL, United States
- Daniel Bailey
- University of Florida, Gainesville, FL, United States
- Daniel Wentworth
- University of Florida, Gainesville, FL, United States
- Chi Van
- University of Florida, Gainesville, FL, United States
- Justin Schwartz
- University of Florida, Gainesville, FL, United States
- Niloofar Dehghan
- The CORE Institute, Phoenix, AZ, United States
- Clifford B. Jones
- The CORE Institute, Phoenix, AZ, United States
- J Tracy Watson
- The CORE Institute, Phoenix, AZ, United States
- Michael McKee
- The CORE Institute, Phoenix, AZ, United States
- Ammar Karim
- The CORE Institute, Phoenix, AZ, United States
- Michael Talerico
- The CORE Institute, Phoenix, AZ, United States
- Debra L. Sietsema
- The CORE Institute, Phoenix, AZ, United States
- Alyse Williams
- The CORE Institute, Phoenix, AZ, United States
- Tayler Dykes
- The CORE Institute, Phoenix, AZ, United States
- William T. Obremskey
- Vanderbilt Medical Center, Nashville, TN, United States
- Amir Alex Jahangir
- Vanderbilt Medical Center, Nashville, TN, United States
- Manish Sethi
- Vanderbilt Medical Center, Nashville, TN, United States
- Robert Boyce
- Vanderbilt Medical Center, Nashville, TN, United States
- Daniel J. Stinner
- Vanderbilt Medical Center, Nashville, TN, United States
- Phillip Mitchell
- Vanderbilt Medical Center, Nashville, TN, United States
- Karen Trochez
- Vanderbilt Medical Center, Nashville, TN, United States
- Andres Rodriguez
- Vanderbilt Medical Center, Nashville, TN, United States
- Vamshi Gajari
- Vanderbilt Medical Center, Nashville, TN, United States
- Elsa Rodriguez
- Vanderbilt Medical Center, Nashville, TN, United States
- Charles Pritchett
- Vanderbilt Medical Center, Nashville, TN, United States
- Christina Boulton
- Banner University Medical Center – Tucson, Tucson, AZ, United States
- Jason Lowe
- Banner University Medical Center – Tucson, Tucson, AZ, United States
- Jason Wild
- Banner University Medical Center – Tucson, Tucson, AZ, United States
- John T. Ruth
- Banner University Medical Center – Tucson, Tucson, AZ, United States
- Michel Taylor
- Banner University Medical Center – Tucson, Tucson, AZ, United States
- Andrea Seach
- Banner University Medical Center – Tucson, Tucson, AZ, United States
- Sabina Saeed
- Banner University Medical Center – Tucson, Tucson, AZ, United States
- Hunter Culbert
- Banner University Medical Center – Tucson, Tucson, AZ, United States
- Alejandro Cruz
- Banner University Medical Center – Tucson, Tucson, AZ, United States
- Thomas Knapp
- Banner University Medical Center – Tucson, Tucson, AZ, United States
- Colin Hurkett
- Banner University Medical Center – Tucson, Tucson, AZ, United States
- Maya Lowney
- Banner University Medical Center – Tucson, Tucson, AZ, United States
- Michael Prayson
- Wright State University, Dayton, OH, United States
- Indresh Venkatarayappa
- Wright State University, Dayton, OH, United States
- Brandon Horne
- Wright State University, Dayton, OH, United States
- Jennifer Jerele
- Wright State University, Dayton, OH, United States
- Linda Clark
- Wright State University, Dayton, OH, United States
- Francesc Marcano-Fernández
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Montsant Jornet-Gibert
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Laia Martínez-Carreres
- Hospital Universitari Parc Tauli, Barcelona, Spain
- David Martí-Garín
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Jorge Serrano-Sanz
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Joel Sánchez-Fernández
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Matsuyama Sanz-Molero
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Alejandro Carballo
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Xavier Pelfort
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Francesc Acerboni-Flores
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Anna Alavedra-Massana
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Neus Anglada-Torres
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Alexandre Berenguer
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Jaume Cámara-Cabrera
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Ariadna Caparros-García
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Ferran Fillat-Gomà
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Ruben Fuentes-López
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Ramona Garcia-Rodriguez
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Nuria Gimeno-Calavia
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Guillem Graells-Alonso
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Marta Martínez-Álvarez
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Patricia Martínez-Grau
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Raúl Pellejero-García
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Ona Ràfols-Perramon
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Juan Manuel Peñalver
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Mònica Salomó Domènech
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Albert Soler-Cano
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Aldo Velasco-Barrera
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Christian Yela-Verdú
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Mercedes Bueno-Ruiz
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Estrella Sánchez-Palomino
- Hospital Universitari Parc Tauli, Barcelona, Spain
- Ernesto Guerra
- Vall d’Hebron Hospital, Barcelona, Spain
- Yaiza García
- Vall d’Hebron Hospital, Barcelona, Spain
- Nicholas M. Romeo
- MetroHealth Medical Center, Cleveland, OH, United States
- Heather A. Vallier
- MetroHealth Medical Center, Cleveland, OH, United States
- Mary A. Breslin
- MetroHealth Medical Center, Cleveland, OH, United States
- Joanne Fraifogl
- MetroHealth Medical Center, Cleveland, OH, United States
- Eleanor S. Wilson
- MetroHealth Medical Center, Cleveland, OH, United States
- Leanne K. Wadenpfuhl
- MetroHealth Medical Center, Cleveland, OH, United States
- Paul G. Halliday
- MetroHealth Medical Center, Cleveland, OH, United States
- Darius G. Viskontas
- FRASER HEALTH AUTHORITY/Royal Columbian Hospital, New Westminster, BC, United States
- Kelly L. Apostle
- FRASER HEALTH AUTHORITY/Royal Columbian Hospital, New Westminster, BC, United States
- Dory S. Boyer
- FRASER HEALTH AUTHORITY/Royal Columbian Hospital, New Westminster, BC, United States
- Farhad O. Moola
- FRASER HEALTH AUTHORITY/Royal Columbian Hospital, New Westminster, BC, United States
- Bertrand H. Perey
- FRASER HEALTH AUTHORITY/Royal Columbian Hospital, New Westminster, BC, United States
- Trevor B. Stone
- FRASER HEALTH AUTHORITY/Royal Columbian Hospital, New Westminster, BC, United States
- H. Michael Lemke
- FRASER HEALTH AUTHORITY/Royal Columbian Hospital, New Westminster, BC, United States
- Mauri Zomar
- FRASER HEALTH AUTHORITY/Royal Columbian Hospital, New Westminster, BC, United States
- Ella Spicer
- FRASER HEALTH AUTHORITY/Royal Columbian Hospital, New Westminster, BC, United States
- Chen “Brenda” Fan
- FRASER HEALTH AUTHORITY/Royal Columbian Hospital, New Westminster, BC, United States
- Kyrsten Payne
- FRASER HEALTH AUTHORITY/Royal Columbian Hospital, New Westminster, BC, United States
- Kevin Phelps
- Carolinas Medical Center, Atrium Health Musculoskeletal Institute, Charlotte, NC, United States
- Michael Bosse
- Carolinas Medical Center, Atrium Health Musculoskeletal Institute, Charlotte, NC, United States
- Madhav Karunakar
- Carolinas Medical Center, Atrium Health Musculoskeletal Institute, Charlotte, NC, United States
- Laurence Kempton
- Carolinas Medical Center, Atrium Health Musculoskeletal Institute, Charlotte, NC, United States
- Stephen Sims
- Carolinas Medical Center, Atrium Health Musculoskeletal Institute, Charlotte, NC, United States
- Joseph Hsu
- Carolinas Medical Center, Atrium Health Musculoskeletal Institute, Charlotte, NC, United States
- Rachel Seymour
- Carolinas Medical Center, Atrium Health Musculoskeletal Institute, Charlotte, NC, United States
- Christine Churchill
- Carolinas Medical Center, Atrium Health Musculoskeletal Institute, Charlotte, NC, United States
- Claire Bartel
- Carolinas Medical Center, Atrium Health Musculoskeletal Institute, Charlotte, NC, United States
- Robert Miles Mayberry
- Carolinas Medical Center, Atrium Health Musculoskeletal Institute, Charlotte, NC, United States
- Maggie Brownrigg
- Carolinas Medical Center, Atrium Health Musculoskeletal Institute, Charlotte, NC, United States
- Cara Girardi
- Carolinas Medical Center, Atrium Health Musculoskeletal Institute, Charlotte, NC, United States
- Ada Mayfield
- Carolinas Medical Center, Atrium Health Musculoskeletal Institute, Charlotte, NC, United States
- Robert A. Hymes
- Inova Fairfax Medical Campus, Falls Church, VA, United States
- Cary C. Schwartzbach
- Inova Fairfax Medical Campus, Falls Church, VA, United States
- Jeff E. Schulman
- Inova Fairfax Medical Campus, Falls Church, VA, United States
- A. Stephen Malekzadeh
- Inova Fairfax Medical Campus, Falls Church, VA, United States
- Michael A. Holzman
- Inova Fairfax Medical Campus, Falls Church, VA, United States
- Lolita Ramsey
- Inova Fairfax Medical Campus, Falls Church, VA, United States
- James S. Ahn
- Inova Fairfax Medical Campus, Falls Church, VA, United States
- Farhanaz Panjshiri
- Inova Fairfax Medical Campus, Falls Church, VA, United States
- Sharmistha Das
- Inova Fairfax Medical Campus, Falls Church, VA, United States
- Antoinisha D. English
- Inova Fairfax Medical Campus, Falls Church, VA, United States
- Sharon M. Haaser
- Inova Fairfax Medical Campus, Falls Church, VA, United States
- Jaslynn A.N. Cuff
- Inova Fairfax Medical Campus, Falls Church, VA, United States
- Holly Pilson
- Wake Forest Baptist Health, Winston-Salem, NC, United States
- Eben A. Carroll
- Wake Forest Baptist Health, Winston-Salem, NC, United States
- Jason J. Halvorson
- Wake Forest Baptist Health, Winston-Salem, NC, United States
- Sharon Babcock
- Wake Forest Baptist Health, Winston-Salem, NC, United States
- J. Brett Goodman
- Wake Forest Baptist Health, Winston-Salem, NC, United States
- Martha B. Holden
- Wake Forest Baptist Health, Winston-Salem, NC, United States
- Debra Bullard
- Wake Forest Baptist Health, Winston-Salem, NC, United States
- Wendy Williams
- Wake Forest Baptist Health, Winston-Salem, NC, United States
- Thomas F. Higgins
- University of Utah, Salt Lake City, UT, United States
- Justin M. Haller
- University of Utah, Salt Lake City, UT, United States
- David L. Rothberg
- University of Utah, Salt Lake City, UT, United States
- Ashley Neese
- University of Utah, Salt Lake City, UT, United States
- Mark Russell
- University of Utah, Salt Lake City, UT, United States
- I. Leah Gitajn
- Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States
- Marcus Coe
- Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States
- Kevin Dwyer
- Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States
- Devin S. Mullin
- Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States
- Clifford A. Reilly
- Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States
- Peter DePalo
- Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States
- Amy E. Hall
- Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States
- Marilyn Heng
- Massachusetts General Hospital, Boston, MA, United States
- Mitchel B. Harris
- Massachusetts General Hospital, Boston, MA, United States
- R. Malcolm Smith
- Massachusetts General Hospital, Boston, MA, United States
- David W. Lhowe
- Massachusetts General Hospital, Boston, MA, United States
- John G. Esposito
- Massachusetts General Hospital, Boston, MA, United States
- Mira Bansal
- Massachusetts General Hospital, Boston, MA, United States
- Patrick F. Bergin
- University of Mississippi Medical Center, Jackson, MS, United States
- George V. Russell
- University of Mississippi Medical Center, Jackson, MS, United States
- Matthew L. Graves
- University of Mississippi Medical Center, Jackson, MS, United States
- John Morellato
- University of Mississippi Medical Center, Jackson, MS, United States
- Heather K. Champion
- University of Mississippi Medical Center, Jackson, MS, United States
- Leslie N. Johnson
- University of Mississippi Medical Center, Jackson, MS, United States
- Sheketha L. McGee
- University of Mississippi Medical Center, Jackson, MS, United States
- Eldrin L. Bhanat
- University of Mississippi Medical Center, Jackson, MS, United States
- Samir Mehta
- University of Pennsylvania, Philadelphia, PA, United States
- Derek Donegan
- University of Pennsylvania, Philadelphia, PA, United States
- Jaimo Ahn
- University of Pennsylvania, Philadelphia, PA, United States
- Annamarie Horan
- University of Pennsylvania, Philadelphia, PA, United States
- Mary Dooley
- University of Pennsylvania, Philadelphia, PA, United States
- Ashley Kuczinski
- University of Pennsylvania, Philadelphia, PA, United States
- Ashley Iwu
- University of Pennsylvania, Philadelphia, PA, United States
- David Potter
- Sanford Health, Sioux Falls, SD, United States
- Robert VanDemark, III
- Sanford Health, Sioux Falls, SD, United States
- Branden Pfaff
- Sanford Health, Sioux Falls, SD, United States
- Troy Hollinsworth
- Sanford Health, Sioux Falls, SD, United States
- Michael J. Weaver
- Brigham Women's Hospital, Boston, MA, United States
- Arvind G. von Keudell
- Brigham Women's Hospital, Boston, MA, United States
- Michael F. McTague
- Brigham Women's Hospital, Boston, MA, United States
- Elizabeth M. Allen
- Brigham Women's Hospital, Boston, MA, United States
- Todd Jaeblon
- University of Maryland Prince George's Capital Region Health, Cheverly, MD, United States
- Robert Beer
- University of Maryland Prince George's Capital Region Health, Cheverly, MD, United States
- Haley K. Demyanovich
- University of Maryland Prince George's Capital Region Health, Cheverly, MD, United States
- Mark J. Gage
- Duke University Hospital, Durham, NC, United States
- Rachel M. Reilly
- Duke University Hospital, Durham, NC, United States
- Cindy Sparrow
- Duke University Hospital, Durham, NC, United States
- Journal volume & issue
-
Vol. 21
p. 100730
Abstract
Introduction: Pragmatic trials in comparative effectiveness research assess the effects of different treatment, therapeutic, or healthcare options in clinical practice. They are characterized by broad eligibility criteria and large sample sizes, which can lead to an unmanageable number of participants, increasing the risk of bias and affecting the integrity of the trial. We describe the development of a sampling strategy tool and its use in the PREPARE trial to circumvent the challenge of unmanageable work flow. Methods: Given the broad eligibility criteria and high fracture volume at participating clinical sites in the PREPARE trial, a pragmatic sampling strategy was needed. Using data from PREPARE, descriptive statistics were used to describe the use of the sampling strategy across clinical sites. A Chi-square test was performed to explore whether use of the sampling strategy was associated with a reduction in the number of missed eligible patients. Results: 7 of 20 clinical sites (35%) elected to adopt a sampling strategy. There were 1539 patients excluded due to the use of the sampling strategy, which represents 30% of all excluded patients and 20% of all patients screened for participation. Use of the sampling strategy was associated with lower odds of missed eligible patients (297/4545 (6.5%) versus 341/3200 (10.7%) p < 0.001). Conclusions: Implementing a sampling strategy in the PREPARE trial has helped to limit the number of missed eligible patients. This sampling strategy represents a simple, easy to use tool for managing work flow at clinical sites and maintaining the integrity of a large trial.
