Fecal microbiota transplantation in a patient hospitalized in the intensive care unit – Case report
Katarzyna Oliwa-Libumska,
Aleksandra Jaworska-Czerwinska,
Malgorzata Mallek-Grabowska,
Robert Wlodarski,
Przemyslaw Zuratynski,
Bartosz Kozlowski
Affiliations
Katarzyna Oliwa-Libumska
Anaesthesiology and Intensive Care Unit, 10th Military Research Hospital and Polyclinic, Powstancow Warszawy 5, 85-681 Bydgoszcz, Poland; Nicolaus Copernicus University in Torun, Collegium Medicum in Bydgoszcz, Faculty of Health Sciences, Department of Emergency Medical Services, M. Curie Sklodowskiej 9, 85-094 Bydgoszcz, Poland
Aleksandra Jaworska-Czerwinska
Anaesthesiology and Intensive Care Unit, 10th Military Research Hospital and Polyclinic, Powstancow Warszawy 5, 85-681 Bydgoszcz, Poland; Nicolaus Copernicus University in Torun, Collegium Medicum in Bydgoszcz, Faculty of Health Sciences, Department of Emergency Medical Services, M. Curie Sklodowskiej 9, 85-094 Bydgoszcz, Poland
Malgorzata Mallek-Grabowska
Anaesthesiology and Intensive Care Unit, 10th Military Research Hospital and Polyclinic, Powstancow Warszawy 5, 85-681 Bydgoszcz, Poland; Faculty of Medicine, Bydgoszcz University of Science and Technology, Aleje Prof. Kaliskiego 7, 85-796 Bydgoszcz, Poland
Robert Wlodarski
Anaesthesiology and Intensive Care Unit, 10th Military Research Hospital and Polyclinic, Powstancow Warszawy 5, 85-681 Bydgoszcz, Poland; Faculty of Medicine, Bydgoszcz University of Science and Technology, Aleje Prof. Kaliskiego 7, 85-796 Bydgoszcz, Poland
Przemyslaw Zuratynski
Nicolaus Copernicus University in Torun, Collegium Medicum in Bydgoszcz, Faculty of Health Sciences, Department of Emergency Medical Services, M. Curie Sklodowskiej 9, 85-094 Bydgoszcz, Poland
Bartosz Kozlowski
Anaesthesiology and Intensive Care Unit, 10th Military Research Hospital and Polyclinic, Powstancow Warszawy 5, 85-681 Bydgoszcz, Poland; Faculty of Medicine, Bydgoszcz University of Science and Technology, Aleje Prof. Kaliskiego 7, 85-796 Bydgoszcz, Poland; Corresponding author. Anaesthesiology and Intensive Care Unit, 10th Military Research Hospital and Polyclinic, Powstancow Warszawy 5, 85-681 Bydgoszcz, Poland.
Clostridioides difficile infections are difficult and serious problem occurring in patients staying in intensive care units. In recent years, the number and severity of these infections, as well as the mortality rate, have been increasing, posing a serious epidemiological problem. This is caused, among other factors, by stressors, artificial nutrition, and sepsis, which lead to disturbances in the patients’ microbiome. Basic method of treatment is antibiotic therapy, however some patients experience recurrences of the infection. Fecal Microbiota Transplantation (FMT) is one of the alternative methods used in treating recurring infections of Clostridioides difficile etiology (Clostridioides Difficile Infection, CDI). The presented case refers to a patient with severe pseudomembranous enterocolitis who underwent FMT twice. This report highlights the role of FMT in the treatment of severe Clostridioides difficile infections in critically ill patients.
