Nature Communications (Mar 2018)

The choroid plexus is an important circadian clock component

  • Jihwan Myung,
  • Christoph Schmal,
  • Sungho Hong,
  • Yoshiaki Tsukizawa,
  • Pia Rose,
  • Yong Zhang,
  • Michael J. Holtzman,
  • Erik De Schutter,
  • Hanspeter Herzel,
  • Grigory Bordyugov,
  • Toru Takumi

DOI
https://doi.org/10.1038/s41467-018-03507-2
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 13

Abstract

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The suprachiasmatic nucleus (SCN) has been thought of as the master circadian clock, but peripheral circadian clocks do exist. Here, the authors show that the choroid plexus displays oscillations more robust than the SCN and that can be described as a Poincaré oscillator with negative twist.