Nature Communications (Jun 2019)

A striatal interneuron circuit for continuous target pursuit

  • Namsoo Kim,
  • Haofang E. Li,
  • Ryan N. Hughes,
  • Glenn D. R. Watson,
  • David Gallegos,
  • Anne E. West,
  • Il Hwan Kim,
  • Henry H. Yin

DOI
https://doi.org/10.1038/s41467-019-10716-w
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 14

Abstract

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Many natural behaviours involve tracking of a target in space. Here, the authors describe a task to assess this behaviour in mice and use in vivo electrophysiology, calcium imaging, optogenetics, and chemogenetics to investigate the role of the striatum in target pursuit.