Antifungal Activity of Soil Streptomyces Isolates Against Cryptococcus neoformans

Abstract

In this study, 26.5% of 128 different isolates of Streptomyces recovered from soils in Duzce province, Turkey showed antifungal activity against Cryptococcus neoformans ATCC 90112. Considering the diameter of the inhibition zone formed on the agar plate, isolates were divided into four sections: section 1 (5-10 mm, slightly-active); section 2 (11-15 mm, moderately-active), section 3 (16-25 mm, highly-active) and section 4 (26-35 mm, ultra-active). It is determined that 3 isolates in section 4 may be a source of novel antibiotic against Cryptococcosis.

Keywords

• streptomyces
• antifungal aktivite
• cryptococcus neoformans
• streptomyces
• antifungal activity
• cryptococcus neoformans