S175: SINGLE-CELL ANALYSIS REVEALS SOMATIC TP53 MUTATIONS EMERGE IN EARLY PROGENITOR CELLS BUT BECOME ENRICHED IN THE ERYTHROID LINEAGE IN ERCC6L2 DISEASE

• Laura Langohr,
• Ilse Kaaja,
• Suvi Douglas,
• Tuulia Räisänen,
• Sadiksha Adhikari,
• Markus Vähä-Koskela,
• Caroline Heckman,
• Jenni Lahtela,
• Ulla Wartiovaara-Kautto,
• Esa Pitkänen,
• Outi Kilpivaara

Affiliations

Laura Langohr

1 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Finland

Ilse Kaaja

2 Applied Tumor Genomics Research Program, Faculty of Medicine, University of Helsinki, Finland

Suvi Douglas

2 Applied Tumor Genomics Research Program, Faculty of Medicine, University of Helsinki, Finland

Tuulia Räisänen

2 Applied Tumor Genomics Research Program, Faculty of Medicine, University of Helsinki, Finland

Sadiksha Adhikari

1 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Finland

Markus Vähä-Koskela

1 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Finland

Caroline Heckman

1 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Finland

Jenni Lahtela

1 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Finland

Ulla Wartiovaara-Kautto

2 Applied Tumor Genomics Research Program, Faculty of Medicine, University of Helsinki, Finland

Esa Pitkänen

1 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Finland

Outi Kilpivaara

2 Applied Tumor Genomics Research Program, Faculty of Medicine, University of Helsinki, Finland