Quality of life characteristics in assessment of diclofenac and Nise® efficacy in patients with gonarthritis

Abstract

Objective. To study efficacy and safety of diclofenac and Nise® application in pts with gonarthritis. Material and methods. 60 pts with gonarthritis were included (mean age 53,4±9,5 years, mean disease duration 7,4±6,8 years). Quality of life was assessed with 4 questionnaires: Modified Stanford Health Assessment Questionnaire (MHAQ), SF-36, Nottingham Health Profile (NHP), Knee injury and Osteoarthritis Outcome Score (KOOS). 30 pts of group I received diclofenac 75 mg/day, 30 pis of group 11 were treated with Nise® 200 mg/day for 10 days. Multi-vitamins "Decamevitum" and injections of Xantinoli nicotinatis were used as additional treatment. Results. Diclofenac and Nise® showed good analgesic and anti-inflammatory effect. Both provided quality of life improvement in pts with gonarthrosis. Nise® was better tolerated.

Keywords

• diclofenac
• nimesulid
• efficacy
• safety