Coil Combination of Multichannel Single Voxel Magnetic Resonance Spectroscopy with Repeatedly Sampled In Vivo Data
Wanqi Hu,
Huiting Liu,
Dicheng Chen,
Tianyu Qiu,
Hongwei Sun,
Chunyan Xiong,
Jianzhong Lin,
Di Guo,
Hao Chen,
Xiaobo Qu
Affiliations
Wanqi Hu
Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, National Institute for Data Science in Health and Medicine, Xiamen University, Xiamen 361005, China
Huiting Liu
Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, National Institute for Data Science in Health and Medicine, Xiamen University, Xiamen 361005, China
Dicheng Chen
Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, National Institute for Data Science in Health and Medicine, Xiamen University, Xiamen 361005, China
Tianyu Qiu
Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, National Institute for Data Science in Health and Medicine, Xiamen University, Xiamen 361005, China
Hongwei Sun
United Imaging Research Institute of Intelligent Imaging, Beijing 100101, China
Chunyan Xiong
Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, National Institute for Data Science in Health and Medicine, Xiamen University, Xiamen 361005, China
Jianzhong Lin
Magnetic Resonance Center, Zhongshan Hospital, Xiamen University, Xiamen 361004, China
Di Guo
School of Computer and Information Engineering, Xiamen University of Technology, Xiamen 361024, China
Hao Chen
School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China
Xiaobo Qu
Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, National Institute for Data Science in Health and Medicine, Xiamen University, Xiamen 361005, China
Magnetic resonance spectroscopy (MRS), as a noninvasive method for molecular structure determination and metabolite detection, has grown into a significant tool in clinical applications. However, the relatively low signal-to-noise ratio (SNR) limits its further development. Although the multichannel coil and repeated sampling are commonly used to alleviate this problem, there is still potential room for promotion. One possible improvement way is combining these two acquisition methods so that the complementary of them can be well utilized. In this paper, a novel coil-combination method, average smoothing singular value decomposition, is proposed to further improve the SNR by introducing repeatedly sampled signals into multichannel coil combination. Specifically, the sensitivity matrix of each sampling was pretreated by whitened singular value decomposition (WSVD), then the smoothing was performed along the repeated samplings’ dimension. By comparing with three existing popular methods, Brown, WSVD, and generalized least squares, the proposed method showed better performance in one phantom and 20 in vivo spectra.
