Nature Communications (Jul 2021)
Renewable fatty acid ester production in Clostridium
- Jun Feng,
- Jie Zhang,
- Yuechao Ma,
- Yiming Feng,
- Shangjun Wang,
- Na Guo,
- Haijiao Wang,
- Pixiang Wang,
- Pablo Jiménez-Bonilla,
- Yanyan Gu,
- Junping Zhou,
- Zhong-Tian Zhang,
- Mingfeng Cao,
- Di Jiang,
- Shuning Wang,
- Xian-Wei Liu,
- Zengyi Shao,
- Ilya Borovok,
- Haibo Huang,
- Yi Wang
Affiliations
- Jun Feng
- Department of Biosystems Engineering, Auburn University
- Jie Zhang
- Department of Biosystems Engineering, Auburn University
- Yuechao Ma
- Department of Biosystems Engineering, Auburn University
- Yiming Feng
- Department of Food Science and Technology, Virginia Tech
- Shangjun Wang
- Department of Biosystems Engineering, Auburn University
- Na Guo
- Department of Biosystems Engineering, Auburn University
- Haijiao Wang
- Department of Biosystems Engineering, Auburn University
- Pixiang Wang
- Department of Biosystems Engineering, Auburn University
- Pablo Jiménez-Bonilla
- Department of Biosystems Engineering, Auburn University
- Yanyan Gu
- Department of Biosystems Engineering, Auburn University
- Junping Zhou
- Department of Biosystems Engineering, Auburn University
- Zhong-Tian Zhang
- Department of Biosystems Engineering, Auburn University
- Mingfeng Cao
- Department of Chemical and Biological Engineering, Iowa State University
- Di Jiang
- Department of Applied Chemistry, University of Science and Technology of China
- Shuning Wang
- State Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University
- Xian-Wei Liu
- Department of Applied Chemistry, University of Science and Technology of China
- Zengyi Shao
- Department of Chemical and Biological Engineering, Iowa State University
- Ilya Borovok
- The Shmunis School of Biomedicine and Cancer Research, Faculty of Life Sciences, Tel Aviv University, Ramat Aviv
- Haibo Huang
- Department of Food Science and Technology, Virginia Tech
- Yi Wang
- Department of Biosystems Engineering, Auburn University
- DOI
- https://doi.org/10.1038/s41467-021-24038-3
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 13
Abstract
Esters can be used as fuels and specialty chemicals for food flavoring, cosmetic and pharmaceutical industries. Here, the authors systematically engineer clostridia, including discovery and deletion of prophages to increase strain stability, for the production of butyl acetate and butyl butyrate from corn stover at low cost.