Nature Communications (Jul 2021)

Renewable fatty acid ester production in Clostridium

  • Jun Feng,
  • Jie Zhang,
  • Yuechao Ma,
  • Yiming Feng,
  • Shangjun Wang,
  • Na Guo,
  • Haijiao Wang,
  • Pixiang Wang,
  • Pablo Jiménez-Bonilla,
  • Yanyan Gu,
  • Junping Zhou,
  • Zhong-Tian Zhang,
  • Mingfeng Cao,
  • Di Jiang,
  • Shuning Wang,
  • Xian-Wei Liu,
  • Zengyi Shao,
  • Ilya Borovok,
  • Haibo Huang,
  • Yi Wang

DOI
https://doi.org/10.1038/s41467-021-24038-3
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 13

Abstract

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Esters can be used as fuels and specialty chemicals for food flavoring, cosmetic and pharmaceutical industries. Here, the authors systematically engineer clostridia, including discovery and deletion of prophages to increase strain stability, for the production of butyl acetate and butyl butyrate from corn stover at low cost.