Journal of Pharmacy and Bioallied Sciences (Dec 2024)
Analyzing Predictive Indicators of Fever and Sepsis after Percutaneous Nephrolithotomy
Abstract
Aim: Our research aims to identify the factors that can help reduce the risk of complications and enhance patient safety. Material and Methods: This was a single institutional, retrospective study over a period of 1 year. A total of 250 patients were included in the study, and the study variables recorded were analyzed statistically. Results: A total of 115 patients presented with stones larger than 25 millimeters, while 75 patients were diagnosed with staghorn stones. Our study revealed a statistical connection between severe sepsis following surgery and three key factors: stone size exceeding 25 millimeters, an operative duration longer than 120 minutes, and substantial bleeding that necessitated a transfusion. Conclusion: Experiencing a fever after PCNL is a common response; however, the likelihood of it developing into a serious condition, such as life-threatening severe sepsis and MODS, is quite low.
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