Canadian Journal of Gastroenterology (Jan 2009)
Pyrosequencing Assay to Rapidly Detect Clarithromycin Resistance Mutations in Canadian Helicobacter pylori Isolates
Abstract
BACKGROUND: Mutations at positions 2142 or 2143 in the two-copy 23S ribosomal RNA gene of Helicobacter pylori are highly predictive of in vitro clarithromycin resistance and failure of clarithromycin-containing treatment regimens.