TRIM25 contributes to the malignancy of acute myeloid leukemia and is negatively regulated by microRNA-137
Wang Sheng,
Zhang Bang Shuo,
Yang Yi,
Li Ying,
Lv Jing Long,
Cheng Yu
Affiliations
Wang Sheng
Department of Hematology, Three Gorges Hospital Affiliated to Chongqing University, Chongqing, 404000, China
Zhang Bang Shuo
Department of Hematology, Three Gorges Hospital Affiliated to Chongqing University, Chongqing, 404000, China
Yang Yi
Department of Hematology, Three Gorges Hospital Affiliated to Chongqing University, Chongqing, 404000, China
Li Ying
Department of Hematology, Three Gorges Hospital Affiliated to Chongqing University, Chongqing, 404000, China
Lv Jing Long
Department of Hematology, Three Gorges Hospital Affiliated to Chongqing University, Chongqing, 404000, China
Cheng Yu
Department of Gastroenterology, Three Gorges Hospital Affiliated to Chongqing University, No. 165 Xincheng Road, Wanzhou District, Chongqing, 404000, China
Acute myeloid leukemia (AML) is a ubiquitous malignancy that occurs in the hematological system. Tripartite motif-containing 25 (TRIM25) has been found to be involved in various carcinomas comprising AML. However, the function and underlying causative role of TRIM25 in AML are still obscure.
