TRIM25 contributes to the malignancy of acute myeloid leukemia and is negatively regulated by microRNA-137

Wang Sheng; Zhang Bang Shuo; Yang Yi; Li Ying; Lv Jing Long; Cheng Yu

doi:10.1515/med-2021-0003

Open Medicine (Dec 2020)

TRIM25 contributes to the malignancy of acute myeloid leukemia and is negatively regulated by microRNA-137

Wang Sheng,
Zhang Bang Shuo,
Yang Yi,
Li Ying,
Lv Jing Long,
Cheng Yu

Affiliations

Wang Sheng: Department of Hematology, Three Gorges Hospital Affiliated to Chongqing University, Chongqing, 404000, China
Zhang Bang Shuo: Department of Hematology, Three Gorges Hospital Affiliated to Chongqing University, Chongqing, 404000, China
Yang Yi: Department of Hematology, Three Gorges Hospital Affiliated to Chongqing University, Chongqing, 404000, China
Li Ying: Department of Hematology, Three Gorges Hospital Affiliated to Chongqing University, Chongqing, 404000, China
Lv Jing Long: Department of Hematology, Three Gorges Hospital Affiliated to Chongqing University, Chongqing, 404000, China
Cheng Yu: Department of Gastroenterology, Three Gorges Hospital Affiliated to Chongqing University, No. 165 Xincheng Road, Wanzhou District, Chongqing, 404000, China

DOI: https://doi.org/10.1515/med-2021-0003
Journal volume & issue: Vol. 16, no. 1
pp. 095 – 103

Abstract

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Acute myeloid leukemia (AML) is a ubiquitous malignancy that occurs in the hematological system. Tripartite motif-containing 25 (TRIM25) has been found to be involved in various carcinomas comprising AML. However, the function and underlying causative role of TRIM25 in AML are still obscure.

Published in Open Medicine

ISSN: 2391-5463 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine
Website: https://www.degruyter.com/journal/key/med/html

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