Early markers of glycaemic control in children with type 1 diabetes mellitus.

Abstract

BackgroundType 1 diabetes mellitus (T1DM) may lead to severe long-term health consequences. In a longitudinal study, we aimed to identify factors present at diagnosis and 6 months later that were associated with glycosylated haemoglobin (HbA(1c)) levels at 24 months after T1DM diagnosis, so that diabetic children at risk of poor glycaemic control may be identified.Methods229 children ResultsFactors at diagnosis that were associated with higher HbA(1c) levels at 6 months: female sex (pConclusionsDeterioration in glycaemic control shortly after diagnosis in diabetic children is particularly marked in Pacific Island children and in those not living with both biological parents. Clinicians need to be aware of factors associated with poor glycaemic control beyond the remission phase, so that more effective measures can be implemented shortly after diagnosis to prevent deterioration in diabetes control.