Journal of Holistic Integrative Pharmacy (Mar 2023)

Clinical analysis of the efficacy of thalidomide combined with finger pointing in the treatment of ankylosing spondylitis

  • Liangyi QIN,
  • Jing LAI

DOI
https://doi.org/10.1016/s2707-3688(23)00095-x
Journal volume & issue
Vol. 4, no. 1
pp. 62 – 67

Abstract

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Objective: This study aims to investigate the different treatment protocols for ankylosing spondylitis (AS) in the clinic. In this paper, finger point therapy and thalidomide were proposed to be used in the treatment of the disease, and the effects were evaluated. Methods: Sixty-eight patients with AS were randomly divided into two groups: the control group and the treatment group, with 34 cases in each group. The two groups were given different medication regimens to compare the differences in symptoms and signs and efficacy after different regimens were implemented. Results: After treatment, the experimental outcomes of the Schober test, occipital wall distance, finger-ground test, blood sedimentation, C-reactive protein, IL-6, TNF-α, and ASDAS index level in the treatment group were significantly different from those in the control group (P<0.05), and the treatment group's overall effective rate was 100% significantly higher than that of the control group (χ2=7.988, P< 0.05). Conclusion: The symptoms and signs of patients with AS could be significantly improved by thalidomide with finger point therapy.

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