PLoS ONE (Jan 2018)

Investigation of quercetin and hyperoside as senolytics in adult human endothelial cells.

  • HyunTae V Hwang,
  • Darlene Thuy Tran,
  • Michelle Nicole Rebuffatti,
  • Chin-Shang Li,
  • Anne A Knowlton

DOI
https://doi.org/10.1371/journal.pone.0190374
Journal volume & issue
Vol. 13, no. 1
p. e0190374

Abstract

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Previously, quercetin has been reported to be a senolytic, a drug that selectively removes senescent cells, in HUVECs. However, we found neither quercetin nor Q3G was effective as a senolytic for adult human endothelial cells.