Molecules (Oct 2014)

Five New Taraxerene-Type Triterpenes from the Branch Barks of Davidia involucrata

  • Qing-Wei Tan,
  • Ming-An Ouyang,
  • Qi-Jian Chen,
  • Zu-Jian Wu

DOI
https://doi.org/10.3390/molecules191117619
Journal volume & issue
Vol. 19, no. 11
pp. 17619 – 17631

Abstract

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Five new taraxerene-type triterpenes, 2-nor-D-friedoolean-14-en-28-ol (1), 2-nor-d-friedoolean-14-en-3α,28-diol (2), 6α-hydroxy-2-nor-D-friedoolean-14-en-3,21-dione (3), 6α,11α,29-trihydroxy-D-friedoolean-14-en-3,16,21-trione (4), and 6α,23,29-trihydroxy-D-friedoolean-14-en-3,16,21-trione (5), were isolated from the MeOH extract of the branch barks of Davidia involucrata, together with five known compounds. Their structures were elucidated by means of various spectroscopic analyses. Five of the identified compounds showed moderate cytotoxicities against the cell proliferation of SGC-7901, MCF-7, and BEL-7404.

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