Synthesis, Structure, Biological Activity, and Luminescence Properties of a “Butterfly”-Type Silver Cluster with 3-Benzyl-4-phenyl-1,2,4-triazol-5-thiol
Dmitriy S. Yambulatov,
Irina A. Lutsenko,
Dmitry E. Baravikov,
Fedor M. Dolgushin,
Tatiana V. Astaf’eva,
Olga B. Bekker,
Lusik G. Nersisyan,
Melanya A. Samvelyan,
Tariel V. Ghochikyan,
Mikhail A. Kiskin,
Igor L. Eremenko,
Vladimir K. Ivanov
Affiliations
Dmitriy S. Yambulatov
Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, 31 Leninsky Prosp., 119991 Moscow, Russia
Irina A. Lutsenko
Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, 31 Leninsky Prosp., 119991 Moscow, Russia
Dmitry E. Baravikov
Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, 31 Leninsky Prosp., 119991 Moscow, Russia
Fedor M. Dolgushin
Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, 31 Leninsky Prosp., 119991 Moscow, Russia
Tatiana V. Astaf’eva
Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, 31 Leninsky Prosp., 119991 Moscow, Russia
Olga B. Bekker
Vavilov Institute of General Genetics, Russian Academy of Sciences, Gubkina, 3, 119333 Moscow, Russia
Lusik G. Nersisyan
Faculty of Chemistry, Yerevan State University, 1 A Manoukyan Str., Yerevan 0025, Armenia
Melanya A. Samvelyan
Faculty of Chemistry, Yerevan State University, 1 A Manoukyan Str., Yerevan 0025, Armenia
Tariel V. Ghochikyan
Faculty of Chemistry, Yerevan State University, 1 A Manoukyan Str., Yerevan 0025, Armenia
Mikhail A. Kiskin
Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, 31 Leninsky Prosp., 119991 Moscow, Russia
Igor L. Eremenko
Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, 31 Leninsky Prosp., 119991 Moscow, Russia
Vladimir K. Ivanov
Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, 31 Leninsky Prosp., 119991 Moscow, Russia
A new silver(I) cluster [Ag8L4(Py)(Pype)]·4Py·11H2O (I) with 3-benzyl-4-phenyl-1,2,4-triazol-5-thiol (L) was synthesized via the direct reaction of AgNO3 and L in MeOH, followed by recrystallization from a pyridine–piperidine mixture. The compound I was isolated in a monocrystal form and its crystal structure was determined via single crystal X-ray diffraction. The complex forms a “butterfly” cluster with triazol-5-thioles. The purity of the silver complex and its stability in the solution was confirmed via NMR analysis. Excitation and emission of the free ligand and its silver complex were studied at room temperature for solid samples. The in vitro biological activity of the free ligand and its complex was studied in relation to the non-pathogenic Mycolicibacterium smegmatis strain. Complexation of the free ligand with silver increases the biological activity of the former by almost twenty times. For the newly obtained silver cluster, a bactericidal effect was established.
