Mineral and bone disorders secondary to chronic kidney disease (renal osteodystrophy)

Abstract

Chronic kidney disease (CKD) in paediatric population gives rise to complex of diseases that is known as chronic kidney disease-mineral and bone disorder (CKD-MBD), which mainly involves the calcium and bone metabolism. Associated rickets and secondary hperparathyroidism leads to pathological changes in the growing bone causing deformities, pathological fractures and growth retardation leading to poor quality of life. Early recognition and proper management can minimize these effects and this care highlights the importance of early diagnosis of proper treatment of CKD in paediatric population.

Keywords

• chronic kidney disease, mineral-bone disorders, secondary hyperparathyroidism, pathological fracture, renal osteodystrophy