Chronic alcohol abuse and spontaneous clearance of hepatitis C virus
Henrique Pott, Junior,
Guilherme Bricks,
Jorge Figueiredo Senise,
Adauto Castelo
Affiliations
Henrique Pott, Junior
Departament of Medicine, Universidade Federal de São Carlos (UFSCar), São Carlos, Brazil; Division of Infectious Diseases, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil; Corresponding author at: Departament of Medicine, Universidade Federal de São Carlos, Rodovia Washington Luis, km 235, São Carlos, SP, 13565-905, Brazil.
Guilherme Bricks
Division of Infectious Diseases, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil
Jorge Figueiredo Senise
Division of Infectious Diseases, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil
Adauto Castelo
Division of Infectious Diseases, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil
Spontaneous clearance of hepatitis C virus (HCV) is an uncommon occurrence in the course of chronic infection. We reported a rare case of a 41-year-old male patient infected with HCV genotype 3a who presented spontaneous viral elimination after increasing his daily consumption of alcoholic beverage. In this short review, we overview how modulation of the hepatic inflammatory response could have a role in the viral elimination process. Keywords: Hepatitis C, Alcohol, Inflammation, Interleukin-10