Selenium-rich Lactobacillus plantarum alleviates salinity stress in Cyprinus carpio: Growth performance, oxidative stress, and immune and inflammatory responses

Xinghua Che; Longwu Geng; Qing Zhang; Haijun Wei; Hailong He; Wei Xu; Xinchi Shang

Aquaculture Reports (Jun 2024)

Selenium-rich Lactobacillus plantarum alleviates salinity stress in Cyprinus carpio: Growth performance, oxidative stress, and immune and inflammatory responses

Xinghua Che,
Longwu Geng,
Qing Zhang,
Haijun Wei,
Hailong He,
Wei Xu,
Xinchi Shang

Affiliations

Xinghua Che: Key Open Laboratory of Cold Water Fish Germplasm Resources and Breeding of Heilongjiang Province, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Harbin 150070, China; Engineering Technology Research Center of Saline-Alkaline Water Fisheries (Harbin), Chinese Academy of Fishery Sciences, Harbin 150070, China
Longwu Geng: Key Open Laboratory of Cold Water Fish Germplasm Resources and Breeding of Heilongjiang Province, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Harbin 150070, China; Engineering Technology Research Center of Saline-Alkaline Water Fisheries (Harbin), Chinese Academy of Fishery Sciences, Harbin 150070, China
Qing Zhang: Key Open Laboratory of Cold Water Fish Germplasm Resources and Breeding of Heilongjiang Province, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Harbin 150070, China; Engineering Technology Research Center of Saline-Alkaline Water Fisheries (Harbin), Chinese Academy of Fishery Sciences, Harbin 150070, China
Haijun Wei: Key Open Laboratory of Cold Water Fish Germplasm Resources and Breeding of Heilongjiang Province, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Harbin 150070, China; Engineering Technology Research Center of Saline-Alkaline Water Fisheries (Harbin), Chinese Academy of Fishery Sciences, Harbin 150070, China
Hailong He: Heilongjiang Aquatic Animal Resource Conservation Center, China
Wei Xu: Key Open Laboratory of Cold Water Fish Germplasm Resources and Breeding of Heilongjiang Province, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Harbin 150070, China; Engineering Technology Research Center of Saline-Alkaline Water Fisheries (Harbin), Chinese Academy of Fishery Sciences, Harbin 150070, China; Corresponding authors at: Key Open Laboratory of Cold Water Fish Germplasm Resources and Breeding of Heilongjiang Province, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Harbin 150070, China.
Xinchi Shang: Key Open Laboratory of Cold Water Fish Germplasm Resources and Breeding of Heilongjiang Province, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Harbin 150070, China; Engineering Technology Research Center of Saline-Alkaline Water Fisheries (Harbin), Chinese Academy of Fishery Sciences, Harbin 150070, China; College of Life Science, Northeast Agricultural University, Harbin 150036, China; Corresponding authors at: Key Open Laboratory of Cold Water Fish Germplasm Resources and Breeding of Heilongjiang Province, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Harbin 150070, China.

Journal volume & issue: Vol. 36
p. 102058

Abstract

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Salinity is an important environmental factor that affects the health of aquatic animals, when salinity level above the tolerance threshold can pose a significant threat to the survival of aquatic animals. As a trace element necessary for animal growth, selenium participates in the body’s antioxidant reaction, and protect aquatic animals from oxidative stress damage. Biological methods for synthesizing selenium nanoparticles (bio-Se-NPs) from bacteria are safe, inexpensive, and accessible. Therefore, we synthesized selenium nanoparticles using Lactobacillus plantarum (probiotic) to study the growth, immune, antioxidant, and inflammatory responses of selenium-rich Lactobacillus plantarum (SL, a type of bio-Se-NPs) fed Cyprinus carpio under low-salinity (5 g/L salinity) and high-salinity (10 g/L salinity) stresses. Analyses revealed that the addition of SL at a concentration of 1 mg/kg significantly alleviated the growth inhibition caused by high-salinity stress. SL significantly alleviated salinity-induced liver tissue injury (numerous cytoplasmic vacuolations the accumulation, inflammatory cell infiltration, nuclear lysis, and some blood congestion). SL significantly alleviated the abnormal levels of serum ALT, AST, GGT and LDH caused by salinity stress, and improved lipid metabolism (TG, TC, LDL-C, HDL-C). SL can also regulates cytokines and antioxidant genes (TNF-α, iL-1β, iL-10, TGFβ-1, SOD, CAT, GPx1, and HO-1) through the NF-κB and Nrf-2 signaling pathways and thereby reduce the inflammatory response and increase the antioxidant level, and these effects attenuate salinity-mediated oxidative damage. In conclusion, our findings indicate that SL can significantly promote the growth and development of fish and alleviate the adverse effects of high-salinity stress and thus, SL can be a potential feed additive for alleviating oxidative stress and inflammatory responses.

Published in Aquaculture Reports

ISSN: 2352-5134 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Agriculture: Aquaculture. Fisheries. Angling
Website: http://www.journals.elsevier.com/aquaculture-reports/

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