Journal of Contemporary Medicine (Mar 2022)
CLINICAL IMPORTANCE OF C-REACTIVE PROTEIN TO ALBUMIN RATIO (CAR) IN COVID-19 PNEUMONIA
Abstract
AIM The course of infection due to SARS-CoV-2 is manifested by viral replication in the upper respiratory tract with or without lung involvement and extrapulmonary systemic hyperinflammation syndrome. Because it has a wide clinical spectrum ranging from asymptomatic cases to multiorgan failure, early identification of prognostic biomarkers is crucial to distinguish patients at risk of developing more serious disease. Our aim is to investigate the relationship between the biomarker CAR, which has both prognostic and diagnostic importance, and Covid 19 infection. MATERİALS AND METHODS Between 1 June 2021 and 1 September 2021, 215 patients who were followed up in the pandemic service and intensive care unit for Covid 19 pneumonia were retrospectively analyzed. The demographic and routine laboratory data of the patients and the parameters accepted as new inflammatory biomarkers such as NLR, PLR, LMR and CAR were compared between the service-intensive care unit and exitus-discharged groups. RESULTS A total of 205 patients with a diagnosis of Covid 19 pneumonia, 113 (55.1%) male and 92 (44.9%) female, were included in the study. When CAR, known as a new inflammatory biomarker, was compared between both groups, it was found to be statistically significantly higher in patients hospitalized in the intensive care unit (p
Keywords