Comparative Study of the Role of MRCP and USG in Patients with Pancreatic Duct and Biliary Duct Pathology

Abstract

Background: Various imaging modalities like USG, CT, Invasive cholangiography has been used since long for the evaluation of the pathology of hepato-biliary-pancreatic duct. These techniques pose some limitations either due to bowel gas and obesity in USG, distal CBD calculus and isodense calculus (isodense to bile) in CT (also not used in patient with history of contrast allergy) and post-procedural complications (followed by invasive cholangiography like ERCP and PTC). MRCP is a non-invasive diagnostic technique for the direct visualization of the biliary ducts images similar to that produced in PTC (percutaneous trans-hepatic cholangiography) and ERCP. Also, the continuous expanding spectrum of therapeutic options, including radiological interventions (for palliative and curative) for the patients with biliary tree pathology requires the accurate assessment of the lesion visualized. Aims & objectives: Comparison of sensitivity, specificity and diagnostic accuracy between the MRCP/MRI and USG in patients with pancreatic and hepato-biliary pathology and it’s related complications. Materials & methods: The study was a retrospective, single institutional study done during the last two years (January 2018 – December 2019) at IGIMS, Patna, Bihar (A tertiary care hospital). Data was collected from the departmental record for USG findings, medical record for history and PACS (Picture archiving and communicating system) for MRCP findings. Hundred patients were included in our study. All the data were entered in the MS Excel sheet and were expressed as percentage and variables as required. Vassarstats software was used for the data analysis. Results: Benign lesions were common in the age range of 46-60 years (23%), followed by 31-45 years. Most of the malignant lesions were detected in the age range of 31-45 years of age group (13%). USG detected and MRCP detected lesions were benign in 63% and 62% of the cases and malignant in 34% and 35% of the cases respectively. There were overlapping findings present in most of the cases. Pancreatitis, cholecystitis and choledochal cysts were usually associated with biliary tree calculi. Overall sensitivity, specificity and diagnostic accuracy of MRI with MRCP sequence (97%, 85% and 92.75%) is greater than that of USG (92%, 80% and 85.5%). Conclusion: MRCP combined with other MRI sequences was superior to the USG in identifying benign and malignant pathology. However, ultrasound remains the primary investigating modality of choice. However, with use of recent advances of USG like harmonic imaging there is significant improvement in the lesion characterization. MRCP is the modality of choice of imaging investigation for the characterization of the lesion especially in obese patients or to choose the patients who are ideal candidate for the MRCP. Keywords: Hepato-biliary-pancreatic pathology, MRCP