Pakistan Veterinary Journal (Jan 2003)
COMPARATIVE EFFICACY OF OXYCLOZANIDE, RAFOXANIDE AND BITHIONOL SULPHOXIDE AGAINST PARAMPHISTOMIASIS IN BUFFALOES
Abstract
In this study comparative anthelmintic trials were conducted using Nilzan drench (Oxyclozanide 3.0% + Levamisole 1.5%), Fasifree (Rafoxanide 3.0%), Irchasol (Bithionol sulphoxide 10% + Levamisole 1.5%) and Nilvenn drench (Levamisole 1.5%) administered orally to compare their efficacy against paramphistomiasis in buffaloes. Seventy five naturally infected buffaloes were selected and divided into five equal groups i.e. A, B. C. D and E with 15 animals in each group. Each animal of group A was given Nilzan (1 ml/2 kg body weight), group B was given Fasifree (1 ml/4 kg) body weight), group C was given Irchasol (1 ml/ 2 kg body weight) group D was given Nilverm (1 ml/2 kg body weight), while group E was kept as untreated control. The efficacy of these anthelmintics was evaluated by counting eggs per grm (EPG) of faeces pre medication (on day zero) and then on day 7, 14 and 21 post medication. The mean efficacy of Nilzan, Fasifree and Irchasol was 97.29 98.5 and 85.56% respectively while Nilverm did not have any effect on Paramphistomiasis in buffaloes.
