First Tonic-Clonic Seizure: Treatment and Prognosis

Abstract

The outcome of immediate treatment (carbamazepine, phenytoin, phenobarbital, or sodium valproate) or delayed treatment after a second seizure, in two groups of patients followed for a minimum of 3 years, was evaluated in a multicenter, randomized, open trial reported by the “FIRST Group” from Segrate, Italy.

Keywords

• first tonic-clonic seizure
• antiepileptic therapy
• rectal diazepam