An Enzymatic Oxidation Cascade Converts δ‑Thiolactone Anthracene to Anthraquinone in the Biosynthesis of Anthraquinone-Fused Enediynes

• Guang-Lei Ma,
• Wan-Qiu Liu,
• Huawei Huang,
• Xin-Fu Yan,
• Wei Shen,
• Surawit Visitsatthawong,
• Kridsadakorn Prakinee,
• Hoa Tran,
• Xiaohui Fan,
• Yong-Gui Gao,
• Pimchai Chaiyen,
• Jian Li,
• Zhao-Xun Liang

Affiliations

Guang-Lei Ma

School of Biological Sciences, Nanyang Technological University, Singapore, Singapore

Wan-Qiu Liu

School of Physical Science and Technology, ShanghaiTech University, Shanghai, China

Huawei Huang

School of Biological Sciences, Nanyang Technological University, Singapore, Singapore

Xin-Fu Yan

School of Biological Sciences, Nanyang Technological University, Singapore, Singapore

Wei Shen

National Key Laboratory of Chinese Medicine Modernization, Innovation Center of Yangtze River Delta, Zhejiang University, Jiaxing, China

Surawit Visitsatthawong

School of Biomolecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology (VISTEC), Wangchan Valley, Rayong, Thailand

Kridsadakorn Prakinee

School of Biomolecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology (VISTEC), Wangchan Valley, Rayong, Thailand

Hoa Tran

School of Biological Sciences, Nanyang Technological University, Singapore, Singapore

Xiaohui Fan

College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China

Yong-Gui Gao

School of Biological Sciences, Nanyang Technological University, Singapore, Singapore

Pimchai Chaiyen

School of Biomolecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology (VISTEC), Wangchan Valley, Rayong, Thailand

Jian Li

School of Physical Science and Technology, ShanghaiTech University, Shanghai, China

Zhao-Xun Liang

School of Biological Sciences, Nanyang Technological University, Singapore, Singapore